Anderson M C, Baer H, Ohman J L
J Allergy Clin Immunol. 1985 Oct;76(4):563-9. doi: 10.1016/0091-6749(85)90776-6.
In direct RAST analyses of sera from 43 individuals with a history of cat allergy, 39.5% were positive to cat pelt, 37.5% to cat saliva, and 12% each to cat urine and serum. The cat pelt and saliva extracts contained allergen 1, but cat serum and cat urine collected by bladder puncture had no detectable levels of this allergen. A crossed immunoelectrophoresis/crossed radioimmunoelectrophoresis analysis failed to reveal any allergen in urine or serum that was not also present in the saliva or pelt preparations, although urine had two allergens not present in serum. When serum from a patient who was direct RAST positive to cat pelt, serum, saliva, and urine was tested by crossed radioimmunoelectrophoresis, it was determined that a total of six allergens were detectable in cat pelt, three in cat urine, and six in cat serum. Since cat serum contains no detectable cat allergen 1, it may be concluded that at least seven allergens derived from the cat are capable of binding to IgE antibody in humans.
在对43名有猫过敏史个体的血清进行直接放射变应原吸附试验（RAST）分析时，39.5%的个体对猫皮屑呈阳性反应，37.5%对猫唾液呈阳性反应，对猫尿液和猫血清呈阳性反应的个体均为12%。猫皮屑和唾液提取物含有变应原1，但通过膀胱穿刺收集的猫血清和猫尿液中未检测到该变应原。交叉免疫电泳/交叉放射免疫电泳分析未能揭示尿液或血清中存在而唾液或皮屑制剂中不存在的任何变应原，尽管尿液中有两种血清中不存在的变应原。当对一名对猫皮屑、血清、唾液和尿液直接RAST呈阳性的患者的血清进行交叉放射免疫电泳检测时，确定在猫皮屑中总共可检测到六种变应原，在猫尿液中可检测到三种，在猫血清中可检测到六种。由于猫血清中未检测到猫变应原1，因此可以得出结论，至少有七种源自猫的变应原能够与人的IgE抗体结合。
