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模拟主动脉壁力学性能的聚合物特性及其在主动脉模型3D打印中的适用性

The Characterization of Polymers That Mimic the Aortic Wall's Mechanical Properties and Their Suitability for Use in the 3D Printing of Aortic Phantoms.

作者信息

Wegner Moritz, Karagoez Benan Sahin, Wippel David, Enzmann Florian K, Niehoff Anja, Salem Oroa, Dorweiler Bernhard

机构信息

Department of Vascular and Endovascular Surgery, Faculty of Medicine, University Hospital Cologne, University of Cologne, Kerpener Strasse 62, 50937 Cologne, Germany.

Department of Vascular Surgery, Medical University Innsbruck, Anichstrasse 35, 6020 Innsbruck, Austria.

出版信息

Polymers (Basel). 2025 Jun 19;17(12):1700. doi: 10.3390/polym17121700.

Abstract

(1) While three-dimensional (3D) printing technology is increasingly being used for the fabrication of high-fidelity, patient-specific aortic models, data on the mechanical properties of polymers are sparse. Therefore, the aim of this study was to identify suitable polymers for this purpose. (2) Methods: Eight flexible polymers, with Shore A hardnesses (ShA) of 27-85, were tested to determine their suitability for PolyJet printing technology. They were tested against porcine aortic and bovine pericardial tissue for suture retention strength, uniaxial stress testing according to ISO 37, and burst pressure in a standardized test setting. (3) Results: The polymers with a ShA of 30-50 showed statistically non-inferior suture retention strength, tensile strength, and burst pressure resistance when compared to pericardial and aortic tissue, respectively. (4) Conclusions: This was the first report to analyze the mechanical properties of eight different flexible PolyJet polymers. We found that the polymers with a Shore A hardness of 30-50 most closely mimicked the mechanical properties of aortic tissue. Therefore, they can be recommended for the additive manufacturing (3D printing) of aortic phantoms for simulation and training purposes.

摘要

(1) 虽然三维(3D)打印技术越来越多地用于制造高保真、患者特异性的主动脉模型,但关于聚合物力学性能的数据却很稀少。因此,本研究的目的是确定适合此目的的聚合物。(2) 方法:测试了八种邵氏A硬度(ShA)为27 - 85的柔性聚合物,以确定它们是否适用于PolyJet打印技术。根据ISO 37标准对它们进行单轴应力测试,并在标准化测试环境中测试其与猪主动脉和牛心包组织相比的缝线保留强度和爆破压力。(3) 结果:与心包和主动脉组织相比,邵氏A硬度为30 - 50的聚合物分别在缝线保留强度、拉伸强度和抗爆破压力方面显示出统计学上的非劣效性。(4) 结论:这是第一份分析八种不同柔性PolyJet聚合物力学性能的报告。我们发现邵氏A硬度为30 - 50的聚合物最接近主动脉组织的力学性能。因此,推荐将它们用于主动脉模型的增材制造(3D打印),以用于模拟和训练目的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9895/12197227/7efc7301a9d9/polymers-17-01700-g001.jpg

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