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在正确的时间出现在正确的地点。

Being in the right place at the right time.

作者信息

Ancoli-Israel Sonia

机构信息

Department of Psychiatry, University of California, San Diego, CA, United States.

出版信息

Sleep Adv. 2025 May 21;6(2):zpaf033. doi: 10.1093/sleepadvances/zpaf033. eCollection 2025 Apr.

Abstract

This paper is a review of my life as a sleep researcher and clinician. I chanced into sleep by being at the right place at the right time. Over the last 45 years, I became an expert on sleep and circadian rhythms in aging, in Alzheimer's disease and Parkinson's disease and in cancer. We were one of the first to show how common sleep apnea and periodic limb movements in sleep are in the elderly. We "moved" into the nursing home and showed how disrupted sleep is in these patients. We used light therapy to improve sleep in the nursing home. We studied the effect of CPAP on sleep and cognition in both Alzheimer's disease and Parkinson's disease. And we were some of the first to study sleep and circadian rhythms in women with breast cancer, starting the evaluations before they started their chemotherapy. These studies were both observational and treatment studies. I am very proud of the work we did. For me, everything revolves around sleep. And that is the beginning of my story.

摘要

本文回顾了我作为一名睡眠研究员和临床医生的职业生涯。我在恰当的时间身处恰当的地点,从而偶然进入了睡眠研究领域。在过去的45年里,我成为了衰老、阿尔茨海默病、帕金森病以及癌症领域中睡眠和昼夜节律方面的专家。我们是最早一批揭示睡眠呼吸暂停和睡眠中周期性肢体运动在老年人中多么常见的人之一。我们走进养老院,展示了这些患者的睡眠是多么紊乱。我们使用光疗法改善养老院患者的睡眠。我们研究了持续气道正压通气(CPAP)对阿尔茨海默病和帕金森病患者睡眠及认知的影响。并且我们是最早一批研究乳腺癌女性的睡眠和昼夜节律的人,在她们开始化疗之前就展开了评估。这些研究既有观察性研究,也有治疗性研究。我为我们所做的工作深感自豪。对我来说,一切都围绕着睡眠展开。而这就是我的故事的开端。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/195c/12199614/0a6b3f2d596c/zpaf033_fig1.jpg

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