Kang Kyumin, Kang Kyung Tae, Kim Yu Cheol
Department of Ophthalmology, Keimyung University School of Medicine, Keimyung University Dongsan Hospital,Daegu, Korea.
Korean J Ophthalmol. 2025 Aug;39(4):330-338. doi: 10.3341/kjo.2024.0122. Epub 2025 Jun 30.
This study assessed the development of macular edema (ME) and its association with systemic diseases in patients with diabetic neovascular glaucoma (NVG).
The medical records of 40 patients (45 eyes) diagnosed with diabetic NVG, between January 2017 and April 2022, were retrospectively reviewed. At the time of NVG diagnosis, central retinal thickness (CRT) was measured using optical coherence tomography. The eyes were categorized into groups with ME (CRT ≥300 μm) and without ME. Systemic diseases, ocular parameters, and prior treatments such as panretinal photocoagulation and intravitreal anti-vascular endothelial growth factor injections were compared between the two groups.
Only 6 of the 45 eyes (13.3%) had ME at the time of NVG diagnosis. No significant differences were observed between the ME and non-ME groups in terms of systemic diseases, including hypertension, hyperlipidemia, ischemic heart disease, cerebrovascular accident, and chronic kidney disease. Other clinical characteristics, such as age, sex, body mass index, smoking history, best-corrected visual acuity, intraocular pressure, lens status, and history of ocular treatment, were also comparable between groups.
In patients with diabetic NVG, ME was observed in a minority of cases and showed no significant association with systemic diseases.
本研究评估了糖尿病性新生血管性青光眼（NVG）患者黄斑水肿（ME）的发生情况及其与全身性疾病的关联。
回顾性分析2017年1月至2022年4月期间诊断为糖尿病性NVG的40例患者（45只眼）的病历。在NVG诊断时，使用光学相干断层扫描测量中央视网膜厚度（CRT）。将这些眼分为有ME（CRT≥300μm）和无ME两组。比较两组之间的全身性疾病、眼部参数以及先前的治疗，如全视网膜光凝和玻璃体内抗血管内皮生长因子注射。
45只眼中只有6只（13.3%）在NVG诊断时存在ME。在全身性疾病方面，包括高血压、高脂血症、缺血性心脏病、脑血管意外和慢性肾脏病，ME组和非ME组之间未观察到显著差异。其他临床特征，如年龄、性别、体重指数、吸烟史、最佳矫正视力、眼压、晶状体状态和眼部治疗史，两组之间也具有可比性。
在糖尿病性NVG患者中，ME仅在少数病例中观察到，且与全身性疾病无显著关联。
