Li Xiaojing, Yang Rong, Gan Pingsheng, Bai Zhijun, Peng Rongfei, Li Juntao, Yuan Jun
Guangzhou Center for Disease Control and Prevention (Guangzhou Health Supervision Institute), Guangzhou 510440, China.
Institute of Public Health, Guangzhou Medical University & Guangzhou Center for Disease Control and Prevention, Guangzhou 510440, China.
Food Chem X. 2025 Jun 10;29:102649. doi: 10.1016/j.fochx.2025.102649. eCollection 2025 Jul.
A simple, rapid, and efficient method was developed for simultaneous determination of 14 PBDEs and 10 NBFRs in animal-derived foods, utilizing gas chromatography-tandem mass spectrometry (GC-MS/MS) coupled with the QuEChERS sample preparation technique. The QuEChERS and GC-MS/MS parameters were carefully optimized for optimal performance. Animal-derived samples were extracted using 10 mL of n-hexane-saturated acetonitrile: Water (1,1, /v) and purified with novel -Sep + sorbent. The optimized method demonstrated excellent linearity, with correlation coefficients exceeding 0.997. Recovery rates for the target analytes in fish, chicken, pork, and beef ranged from 67.6 % to 104.8 %. The limits of detection (LOD) ranged from 3.2 to 62.9 ng/kg, while the limits of quantification (LOQ) varied from 10.7 to 207.6 ng/kg. This method was successfully applied to analyze 227 animal-derived food samples from markets in Guangzhou, China. The results demonstrated that the method is both effective and straightforward for analysis of PBDEs and NBFRs in complex food samples.
建立了一种简单、快速且高效的方法，用于同时测定动物源性食品中的14种多溴二苯醚和10种新型溴代阻燃剂，该方法采用气相色谱-串联质谱法（GC-MS/MS）并结合QuEChERS样品制备技术。对QuEChERS和GC-MS/MS参数进行了仔细优化以实现最佳性能。动物源性样品用10 mL正己烷饱和乙腈：水（1:1，v/v）提取，并用新型-Sep +吸附剂净化。优化后的方法具有出色的线性，相关系数超过0.997。鱼类、鸡肉、猪肉和牛肉中目标分析物的回收率在67.6%至104.8%之间。检测限（LOD）在3.2至62.9 ng/kg之间，定量限（LOQ）在10.7至207.6 ng/kg之间。该方法成功应用于分析来自中国广州市场的227份动物源性食品样品。结果表明，该方法对于分析复杂食品样品中的多溴二苯醚和新型溴代阻燃剂既有效又简便。
