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本文引用的文献

1
Multi-target directed ligands inspired natural products as an effective approach for the treatment of complex chronic health disorders.受天然产物启发的多靶点导向配体是治疗复杂慢性健康疾病的有效方法。
Bioorg Chem. 2025 Jan;154:108075. doi: 10.1016/j.bioorg.2024.108075. Epub 2024 Dec 17.
2
"Several birds with one stone": exploring the potential of AI methods for multi-target drug design.一石多鸟：探索人工智能方法在多靶点药物设计中的潜力
Mol Divers. 2024 Nov 24. doi: 10.1007/s11030-024-11042-0.
3
Molecular hybridization: a powerful tool for multitarget drug discovery.分子杂交：一种用于多靶点药物发现的强大工具。
Expert Opin Drug Discov. 2024 Apr;19(4):451-470. doi: 10.1080/17460441.2024.2322990. Epub 2024 Mar 8.
4
New avenues in artificial-intelligence-assisted drug discovery.人工智能辅助药物发现的新途径。
Drug Discov Today. 2023 Apr;28(4):103516. doi: 10.1016/j.drudis.2023.103516. Epub 2023 Feb 2.
5
The chemistry toolbox of multitarget-directed ligands for Alzheimer's disease.阿尔茨海默病多靶点导向配体的化学工具包。
Eur J Med Chem. 2019 Nov 1;181:111572. doi: 10.1016/j.ejmech.2019.111572. Epub 2019 Aug 1.
6
The Mediterranean Diet as source of bioactive compounds with multi-targeting anti-cancer profile.地中海饮食作为具有多靶点抗癌特性的生物活性化合物的来源。
Eur J Med Chem. 2019 Nov 1;181:111579. doi: 10.1016/j.ejmech.2019.111579. Epub 2019 Jul 31.
7
Editorial: Multi-Target-Directed Ligands (MTDL) as Challenging Research Tools in Drug Discovery: From Design to Pharmacological Evaluation.社论：多靶点导向配体（MTDL）作为药物研发中具有挑战性的研究工具：从设计到药理评估
Front Chem. 2019 Feb 18;7:71. doi: 10.3389/fchem.2019.00071. eCollection 2019.

Editorial: Multi-target drug discovery and design for complex health disorders.

作者信息

Badria Farid A, De Filippis Barbara, El-Magd Mohammed Abu, Elbadawi Mostafa M, Hamdi Abdelrahman, Elgazar Abdullah A

机构信息

Department of Pharmacognosy, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt.

Department of Pharmacy, "G. d'Annunzio" University, Chieti, Italy.

出版信息

Front Pharmacol. 2025 Jun 13;16:1633600. doi: 10.3389/fphar.2025.1633600. eCollection 2025.

DOI:10.3389/fphar.2025.1633600
PMID:40584615
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12202662/
Abstract
摘要