Dipartimento di Scienze della Salute, Università "Magna Græcia", Campus Salvatore Venuta, Viale Europa, 88100, Catanzaro, Italy; Net4Science srl, Università "Magna Græcia", Campus Salvatore Venuta, Viale Europa, 88100, Catanzaro, Italy.
Dipartimento di Scienze della Salute, Università "Magna Græcia", Campus Salvatore Venuta, Viale Europa, 88100, Catanzaro, Italy.
Eur J Med Chem. 2019 Nov 1;181:111579. doi: 10.1016/j.ejmech.2019.111579. Epub 2019 Jul 31.
Many bioactive agents have been extracted from plants or belong to functional foods and have been considered in the treatment of serious and multifactorial diseases, such as cancer. In particular, this review is focused on the anti-cancer properties owned by several natural products typically from the Mediterranean area. In some regions of the South of Italy, a lower cancer incidence has been observed. There is increasing evidence that adherence to a Mediterranean dietary pattern correlates with reduced risk of several cancer types. This could be mainly attributed to the typical lifestyle aspects of the Mediterranean diet, such as high consumption of fruit and vegetables. In this review, the main natural products of the Mediterranean area are discussed, with particular attention on their anti-cancer properties endowed with multi-target profiles.
许多生物活性物质已从植物中提取出来或属于功能性食品，并被认为可用于治疗癌症等严重的多因素疾病。特别是，本次综述主要关注几种天然产物的抗癌特性，这些天然产物通常来自地中海地区。在意大利南部的一些地区，癌症发病率较低。越来越多的证据表明，坚持地中海饮食模式与降低多种癌症类型的风险相关。这主要归因于地中海饮食的典型生活方式方面，例如大量食用水果和蔬菜。在本次综述中，讨论了地中海地区的主要天然产物，特别关注它们具有多靶点特性的抗癌特性。
