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利用低成本传感器和全球定位系统评估华盛顿州双胞胎登记处个人暴露于细颗粒物的时空变化。

Using low-cost sensors and GPS to assess spatiotemporal variations in personal exposure to PM in the Washington State Twin Registry.

作者信息

Liu Ningrui, Avery Ally, Austin Elena, Meschke John S, Beck Nicola K, Carvlin Graeme, Liu Yisi, Moudon Anne V, Novosselov Igor, Shirai Jeffry H, Duncan Glen E, Seto Edmund

机构信息

Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, WA, USA.

Department of Nutrition and Exercise Physiology, Washington State University Health Sciences Spokane, Spokane, WA, USA.

出版信息

medRxiv. 2025 Jun 9:2025.06.09.25329147. doi: 10.1101/2025.06.09.25329147.

Abstract

Epidemiological studies typically rely on exposure assessments based on ambient PM concentrations at participants' home addresses. However, these approaches neglect personal exposures indoors and across different non-residential microenvironments. To address this problem, our study combined low-cost sensors and GPS to conduct two-week personal PM monitoring in 168 adults recruited from the Washington State Twin Registry between 2018 and 2021. PM mass concentration, size-resolved particle number concentration, temperature, humidity, and GPS coordinates were recorded at 1-minute intervals, providing 5,161,737 datapoints. We used GPS coordinates and a processing algorithm for automatic classification of microenvironments, including seven land use types and vehicles, and time spent indoors/outdoors. The low-cost sensors were calibrated in-situ, using regulatory monitoring data within 600 m of participants' outdoor measurements (R = 0.93). A linear mixed model was used to estimate the associations of multiple spatiotemporal factors with personal exposure concentrations. The average PM exposure concentration was 8.1 ± 15.8 μg/m for all participants. Indoor exposure concentration was higher than outdoor exposure level, and indoor exposure dose contributed 77% to the total exposure. Exposures in residential and industrial land use had a higher concentration than in other areas, and accounted for 69% of the total exposure dose. Furthermore, personal exposure concentration was the highest during winter and evening hours, possibly due to cooking and heating-related behaviors. This study demonstrates that personal monitoring can capture spatiotemporal variations in PM exposure more accurately than home-based approaches based on ambient air quality, and suggests opportunities for controlling exposures in certain microenvironments.

摘要

流行病学研究通常依赖于基于参与者家庭住址处环境颗粒物浓度的暴露评估。然而,这些方法忽略了室内以及不同非居住微环境中的个人暴露情况。为了解决这个问题,我们的研究结合了低成本传感器和全球定位系统(GPS),对2018年至2021年间从华盛顿州双胞胎登记处招募的168名成年人进行了为期两周的个人颗粒物监测。以1分钟的间隔记录颗粒物质量浓度、粒径分辨的粒子数浓度、温度、湿度和GPS坐标,共提供了5161737个数据点。我们使用GPS坐标和一种处理算法对微环境进行自动分类,包括七种土地利用类型、车辆以及在室内/室外度过的时间。低成本传感器在现场进行了校准,使用参与者室外测量点600米范围内的监管监测数据(R = 0.93)。采用线性混合模型来估计多个时空因素与个人暴露浓度之间的关联。所有参与者的平均颗粒物暴露浓度为8.1±15.8μg/m³。室内暴露浓度高于室外暴露水平,室内暴露剂量占总暴露量的77%。居住和工业用地的暴露浓度高于其他区域,占总暴露剂量的69%。此外,个人暴露浓度在冬季和夜间最高,这可能与烹饪和取暖相关行为有关。这项研究表明,与基于环境空气质量的家庭监测方法相比,个人监测能够更准确地捕捉颗粒物暴露的时空变化,并为控制某些微环境中的暴露提供了机会。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/94c8/12204440/37d8b77110f9/nihpp-2025.06.09.25329147v1-f0001.jpg

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