Ambient Air Pollution and Smell Function: Evidence from the National Geographic Smell Survey.

BACKGROUND

Olfactory sensory neurons are located outside the brain, allowing them to detect environmental chemicals. However, this comes at the cost of exposure to potential toxins, which may decrease olfactory function.

METHODS

We sought to assess the association between olfactory function and air pollution, measured by the National Geographic Smell Survey and data from the Environmental Protection Agency. We examined the effects of air pollution exposure on perceived odor intensity and identification ability across 97,087 survey respondents assigned air pollution exposures at the zip code level.

RESULTS

The results show that NO, SO, and O were associated with slight alterations in olfactory acuity, and these relationships differed by odor and the type of pollutant. Specifically, increases in annual mean concentration by a standard deviation of NO (OR=0.97; CI=0.96-0.97) and SO (OR=0.99; CI=0.98-1.00) were associated with reduced odor identification ability. Conversely, increases in O concentration were associated with a slight increase in olfactory ability (OR=1.01; CI=1.00-1.02).

CONCLUSIONS

Air quality is associated with olfactory health, underscoring the need to investigate the mechanisms driving pollution-induced impairment.