Piekoszewska-Ziętek Paula, Pańczyk-Tomaszewska Małgorzata, Olczak-Kowalczyk Dorota
Department of Paediatric Dentistry, Medical University of Warsaw, St. Binieckiego 6, Warsaw, 02-097, Poland.
Department of Paediatrics and Nephrology, Medical University of Warsaw, Warsaw, Poland.
Sci Rep. 2025 Jul 1;15(1):21735. doi: 10.1038/s41598-025-06687-2.
This study aimed to evaluate oral hygiene, gingival condition, and the presence of selected periodontal pathogens in children with nephrotic syndrome (NS) compared to healthy controls. The primary research question was whether interdisciplinary care contributes to better oral health in this medically compromised group.A cross-sectional study was conducted among 86 children aged 5-17 years, including 40 patients with NS and 46 healthy controls. Clinical evaluation included the Plaque Index (Pl.I.), Approximal Plaque Index (API), Gingival Index (GI), Bleeding on Probing (BoP), and presence of dental calculus. Periodontal pathogens were identified using the PET Plus microbiological test.Children with NS had better interdental hygiene and a higher proportion of individuals with good oral hygiene. Gingival inflammation indicators (GI, BoP) did not differ significantly between groups. Notably, the prevalence and bacterial load of Treponema denticola and Fusobacterium nucleatum were lower in the NS group. Dental calculus was also less frequently observed in these patients.Despite being a medically vulnerable population, children with nephrotic syndrome under interdisciplinary care demonstrated favorable oral hygiene and reduced colonization by key periodontal pathogens. These findings suggest that systematic dental follow-up integrated with nephrology care may have a protective effect on oral health and help prevent inflammation-associated complications.Implementing regular dental screening within pediatric nephrology care can enhance early intervention, reduce oral disease burden, and support systemic health in children with nephrotic syndrome.
本研究旨在评估与健康对照组相比,肾病综合征(NS)患儿的口腔卫生、牙龈状况及某些牙周病原体的存在情况。主要研究问题是跨学科护理是否有助于改善这一医学上存在健康问题的群体的口腔健康。
对86名5至17岁的儿童进行了一项横断面研究,其中包括40名NS患儿和46名健康对照。临床评估包括菌斑指数(Pl.I.)、邻面菌斑指数(API)、牙龈指数(GI)、探诊出血(BoP)以及牙结石的存在情况。使用PET Plus微生物检测法鉴定牙周病原体。
NS患儿的牙间隙卫生状况较好,口腔卫生良好的个体比例较高。两组之间的牙龈炎症指标(GI、BoP)无显著差异。值得注意的是,NS组中齿垢密螺旋体和具核梭杆菌的患病率和细菌载量较低。这些患者中牙结石的观察频率也较低。
尽管肾病综合征患儿是医学上的弱势群体,但在跨学科护理下,他们表现出良好的口腔卫生状况,关键牙周病原体的定植减少。这些发现表明,与肾病护理相结合的系统性牙科随访可能对口腔健康具有保护作用,并有助于预防炎症相关并发症。
在儿科肾病护理中实施定期牙科筛查可以加强早期干预,减轻口腔疾病负担,并支持肾病综合征患儿的全身健康。