Rabby Md Raisul Islam, Hossain Md Sabbir, Chowdhury Nafisa Nusrat, Akter Fatema, Razu Mamudul Hasan, Ahmed Zabed Bin, Khan Mala
Bangladesh Reference Institute for Chemical Measurements (BRiCM), Dhaka, Bangladesh.
Int J Microbiol. 2025 Jun 24;2025:2602317. doi: 10.1155/ijm/2602317. eCollection 2025.
This study investigates the effectiveness of a disinfectant formulation comprising acetic acid, hydrogen peroxide, and peracetic acid (AAHPA) against , , and on petri plates, smooth surfaces, and rough surfaces. Comparative analysis with conventional disinfectants such as 70% isopropyl alcohol, 1.5% chlorhexidine gluconate, 10% sodium hypochlorite, and 0.2% hydrogen peroxide reveal AAHPA's superior performance, achieving significantly higher log reduction ( < 0.05) and percentage reduction ( < 0.01) against in 5 min on petri plates. On smooth and rough surfaces, AAHPA exhibits exceptional efficacy, demonstrating the highest log and percentage reduction against in 0.5, 1, and 5 min, surpassing other disinfectants. AAHPA shows the highest bacterial decline against and , followed by 0.2% hydrogen peroxide. In some cases, 0.2% hydrogen peroxide was slightly more effective than AAHPA against and in 5 min. Time-dependent analysis of log reduction trends emphasizes AAHPA's rapid and consistent effectiveness, particularly in 0.5 min, positioning it as a promising disinfectant formulation with broad-spectrum efficacy across diverse surfaces.
本研究调查了一种由乙酸、过氧化氢和过氧乙酸（AAHPA）组成的消毒剂配方在培养皿、光滑表面和粗糙表面上对[具体细菌名称缺失]、[具体细菌名称缺失]和[具体细菌名称缺失]的消毒效果。与传统消毒剂如70%异丙醇、1.5%葡萄糖酸氯己定、10%次氯酸钠和0.2%过氧化氢的对比分析表明，AAHPA具有卓越的性能，在培养皿上对[具体细菌名称缺失]在5分钟内实现了显著更高的对数减少（P<0.05）和百分比减少（P<0.01）。在光滑和粗糙表面上，AAHPA表现出卓越的功效，在0.5、1和5分钟内对[具体细菌名称缺失]表现出最高的对数和百分比减少，超过了其他消毒剂。AAHPA对[具体细菌名称缺失]和[具体细菌名称缺失]的细菌下降率最高，其次是0.2%过氧化氢。在某些情况下，0.2%过氧化氢在5分钟内对[具体细菌名称缺失]和[具体细菌名称缺失]的效果略优于AAHPA。对数减少趋势的时间依赖性分析强调了AAHPA快速且一致的有效性，特别是在0.5分钟时，使其成为一种在不同表面具有广谱功效的有前景的消毒剂配方。
