Liu Tingting, Wang Yao, Wang Yuan, Xia Dong
Department of Geriatrics, Beijing Geriatric Hospital, Beijing, 100095, People's Republic of China.
Department of Emergency, Beijing Geriatric Hospital, Beijing, 100095, People's Republic of China.
Clin Interv Aging. 2025 Jun 26;20:895-902. doi: 10.2147/CIA.S518795. eCollection 2025.
This study examined the utility of the phase angle (PhA) in predicting malnutrition risk and 6-month mortality in older patients with multimorbidity.
We conducted a retrospective analysis of 104 hospitalized older adults with multiple chronic conditions. Data on clinical parameters, body composition, and nutritional status (via Nutritional Risk Screening 2002) were analyzed. Pearson's correlation analysis and receiver operating characteristic analysis were used to identify the optimal PhA cutoff for malnutrition risk. Mortality and malnutrition were compared between the low and high PhA groups.
PhA was significantly correlated with age, BMI, hemoglobin, albumin, triglycerides, and the extracellular water/total body water ratio (all < 0.05). The optimal PhA cutoff was 3.15°, which had 62% sensitivity and 79% specificity for malnutrition prediction. Patients in the low PhA group had significantly higher rates of malnutrition (80.85% vs 40.35%, < 0.05) and mortality (29.79% vs 3.5%, < 0.05).
PhA is a clinically valuable tool for assessing malnutrition risk and predicting mortality in older patients with multimorbidity. It enables early identification and intervention, improving patient outcomes.
本研究探讨了相位角（PhA）在预测老年多病患者营养不良风险和6个月死亡率方面的效用。
我们对104名患有多种慢性病的住院老年人进行了回顾性分析。分析了临床参数、身体成分和营养状况（通过2002年营养风险筛查）的数据。采用Pearson相关性分析和受试者工作特征分析来确定营养不良风险的最佳PhA临界值。比较了低PhA组和高PhA组的死亡率和营养不良情况。
PhA与年龄、体重指数、血红蛋白、白蛋白、甘油三酯以及细胞外水/总体水比率显著相关（均P<0.05）。最佳PhA临界值为3.15°，其对营养不良预测的敏感性为62%，特异性为79%。低PhA组患者的营养不良发生率（80.85%对40.35%，P<0.05）和死亡率（29.79%对3.5%，P<0.05）显著更高。
PhA是评估老年多病患者营养不良风险和预测死亡率的一种具有临床价值的工具。它能够实现早期识别和干预，改善患者预后。
