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使用GenePix进行蛋白质微阵列分析。

Protein Microarray Analysis with GenePix.

作者信息

Barderas Rodrigo, Montero-Calle Ana, San Segundo-Acosta Pablo

机构信息

Functional Proteomics Unit, Chronic Disease Programme (UFIEC), Instituto de Salud Carlos III, Madrid, Spain.

CIBER of Frailty and Healthy Aging (CIBERFES), Madrid, Spain.

出版信息

Methods Mol Biol. 2025;2929:85-95. doi: 10.1007/978-1-0716-4595-6_7.

Abstract

Protein microarrays are powerful proteomics tools for high-throughput analysis. They allow to screen simultaneously large numbers of proteins for their binding specificity, enzymatic activity, and abundance in biological samples, among other uses. One widely used platform for protein microarray analysis is GenePix, which offers instrumentation and software solutions for data acquisition and analysis. Here, we provide an overview of the use of GenePix for protein microarray analysis, exploring its applications and advantages.

摘要

蛋白质微阵列是用于高通量分析的强大蛋白质组学工具。它们能够同时筛选生物样品中大量蛋白质的结合特异性、酶活性和丰度等。蛋白质微阵列分析中一种广泛使用的平台是GenePix,它提供用于数据采集和分析的仪器及软件解决方案。在此,我们概述GenePix在蛋白质微阵列分析中的应用,探讨其应用和优势。

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