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爱尔兰可卡因使用趋势及与可卡因相关的危害:一项回顾性多源数据库研究

Trends in cocaine use and cocaine-related harms in Ireland: a retrospective, multi-source database study.

作者信息

Mongan Deirdre, Millar Seán R, Carew Anne Marie, Kelleher Cathy, Daly Antoinette, Lyons Suzi, Galvin Brian, Smyth Bobby P

机构信息

Health Research Board, Dublin, Ireland.

School of Public Health, University College Cork, Cork, Ireland.

出版信息

BMC Public Health. 2025 Jul 2;25(1):2285. doi: 10.1186/s12889-025-23224-y.

Abstract

BACKGROUND

Increased cocaine supply has coincided with increased global cocaine use. In 2019 Ireland had one of the highest last-year rates of cocaine use in Europe. However, there is a lack of data on the health-related impacts of cocaine use in European countries over time.

METHODS

This retrospective, multi-source database study utilised data from national databases to evaluate the following time trends: (1) prevalence of cocaine use; (2) number of cocaine-related hospital discharges; (3) number of cocaine-related psychiatric hospital admissions; (4) treatment demand for problem cocaine use; and (5) cocaine-related deaths. Joinpoint regression was used to examine change points over time and average annual percentage changes (AAPCs).

RESULTS

Last-year cocaine use among 15-64-year-olds increased from 1·1% in 2002/03 to 2·4% in 2022/23. The number of cocaine-related acute hospital discharges per 100,000 population increased from 1·4 in 2000 to 24·3 in 2023 (AAPC: 13·0%; 95% CI: 11·95, 14·84), and psychiatric hospitalisations increased from 0·2 in 2000 to 2·4 in 2022 (AAPC: 11·1%; 95% CI: 9·41, 15·48). Treatment entrants reporting cocaine as a main problem drug increased from 1·5 per 100,000 population in 2000 to 93·2 in 2023 (AAPC: 17·6%; 95% CI: 15·89, 20·74), while cocaine-related deaths increased from 0·3 in 2000 to 5·6 in 2020 (AAPC: 16·9%; 95% CI: 14·71, 21·70). In general, rates of harm increased from 2000 to 2007, decreased until 2011-2013, and since 2013 have increased significantly and consistently.

CONCLUSIONS

Multiple databases show significant increases in cocaine-related harm since 2000. Responding to cocaine-related health problems and prevention efforts focused on cocaine constitute a public health priority.

摘要

背景

可卡因供应的增加与全球可卡因使用量的增加同时出现。2019年,爱尔兰是欧洲去年可卡因使用率最高的国家之一。然而,随着时间的推移,欧洲国家缺乏关于可卡因使用对健康影响的数据。

方法

这项回顾性多源数据库研究利用国家数据库的数据来评估以下时间趋势:(1)可卡因使用的流行率;(2)与可卡因相关的医院出院人数;(3)与可卡因相关的精神病医院入院人数;(4)对可卡因使用问题的治疗需求;以及(5)与可卡因相关的死亡人数。采用连接点回归来检查随时间的变化点和平均年度百分比变化(AAPC)。

结果

15至64岁人群中去年的可卡因使用率从2002/03年的1.1%上升至2022/23年的2.4%。每10万人口中与可卡因相关的急性医院出院人数从2000年的1.4人增加到2023年的24.3人(AAPC:13.0%;95%CI:11.95,14.84),精神病住院人数从2000年的0.2人增加到2022年的2.4人(AAPC:11.1%;95%CI:9.41,15.48)。报告可卡因是主要问题药物的治疗入组人数从2000年每10万人口1.5人增加到2023年的93.2人(AAPC:17.6%;95%CI:15.89,20.74),而与可卡因相关的死亡人数从2000年的0.3人增加到2020年的5.6人(AAPC:16.9%;95%CI:14.71,21.70)。总体而言,危害发生率从2000年到2007年上升,到2011 - 2013年下降,自2013年以来显著且持续上升。

结论

多个数据库显示,自2000年以来,与可卡因相关的危害显著增加。应对与可卡因相关的健康问题以及专注于可卡因的预防工作构成了公共卫生的优先事项。

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