Odoom Theophilus, Abbiw Richard Kwamena, Abuh Joseph Kofi, Allegye-Cudjoe Emmanuel, Johnson Sherry Ama Mawuko, Tasiame William, Arthur Daniel, Anderson Benita, Settypalli Tirumala B K, Lamien Charles E, Dundon William G
Accra Veterinary Laboratory, Veterinary Service Directorate, Accra, Ghana.
School of Veterinary Medicine, CBAS, University of Ghana, Accra, Ghana.
Front Vet Sci. 2025 Jun 18;12:1524562. doi: 10.3389/fvets.2025.1524562. eCollection 2025.
On the 24/09/2023, a video of a suspected rabid bull at a livestock market in Ghana was shared on social media and was seen by a local veterinary officer. This led to an on-site investigation by veterinary authorities on the 25/09/2023 which concluded that the bull had been bitten by a three-month old dog 4 days previously. The puppy, which was killed and buried after the bite, was subsequently exhumed, tested and confirmed positive for rabies. The bull was humanely destroyed. Brain tissue from the bull was collected and sent to the Accra Veterinary Laboratory for further analysis. RABV was confirmed by conventional RT-PCR and the full genome of the viruses from both animals were sequenced. The consensus sequences of the genomes belonging to the Africa 2 clade, were identical although sub-consensus variants in a subset of the sequences located in the RNA-dependent-RNA polymerase (L) gene of the bovine virus were observed. The implication of these findings is discussed.
2023年9月24日，一段关于加纳一个牲畜市场疑似患狂犬病公牛的视频在社交媒体上流传，被当地一名兽医官员看到。这促使兽医当局于2023年9月25日进行了现场调查，调查结论是这头公牛在4天前被一只3个月大的小狗咬伤。这只小狗在咬人后被杀死并埋葬，随后被挖出，经检测确诊感染狂犬病。这头公牛被人道毁灭。采集了公牛的脑组织并送往阿克拉兽医实验室进行进一步分析。通过常规逆转录聚合酶链反应（RT-PCR）确认了狂犬病病毒（RABV），并对两只动物的病毒全基因组进行了测序。属于非洲2进化枝的基因组的一致序列相同，不过在牛病毒的RNA依赖性RNA聚合酶（L）基因中的一部分序列中观察到了亚一致变体。讨论了这些发现的意义。
