Zhao Qianyun, Zhu Yuyu, Jiang Junyi, Wang Deguang
Institute of Nephrology and Inflammatory Immune Diseases, the Second Affiliated Hospital of Anhui Medical University, Hefei, China.
Ann Med. 2025 Dec;57(1):2527359. doi: 10.1080/07853890.2025.2527359. Epub 2025 Jul 3.
This study aims to investigate the influence of the COVID-19 lockdown period on anxiety, anger, loneliness and depression, four categories of negative emotions, in patients undergoing maintenance hemodialysis.
A cross-sectional survey was conducted, and a total of 174 patients receiving maintenance hemodialysis at the Second Affiliated Hospital and Fourth Affiliated Hospital Hemodialysis Center of Anhui Medical University between October 20 and October 27, 2022, were selected as the study subjects. We used the Medical Staff Stress and Negative Emotions Scale (MSSNS) to assess the emotional changes in anxiety, anger, loneliness and depression in these patients before and during the lockdown.
A total of 174 questionnaires were collected, all of which were valid. During the lockdown period, the scores for anxiety (18.89 ± 6.83), anger (10.20 ± 3.32), loneliness (10.86 ± 3.81) and depression (14.13 ± 4.24) were significantly higher than the scores before the lockdown for anxiety (16.63 ± 4.64), anger (9.74 ± 2.60), loneliness (10.26 ± 3.35) and depression (13.11 ± 4.24). These differences were statistically significant ( < 0.001).
During the COVID-19 lockdown, patients undergoing maintenance hemodialysis experienced significantly higher levels of anxiety, anger, loneliness and depression compared to the pre-lockdown period. Our study emphasizes the importance of paying sufficient attention to the mental health of hemodialysis patients during such public health crises.
本研究旨在调查2019年冠状病毒病（COVID-19）封锁期对维持性血液透析患者焦虑、愤怒、孤独和抑郁这四类负面情绪的影响。
进行了一项横断面调查，选取2022年10月20日至10月27日期间在安徽医科大学第二附属医院和第四附属医院血液透析中心接受维持性血液透析的174例患者作为研究对象。我们使用医务人员压力与负面情绪量表（MSSNS）评估这些患者在封锁前和封锁期间焦虑、愤怒、孤独和抑郁方面的情绪变化。
共收集到174份问卷，均有效。在封锁期间，焦虑（18.89±6.83）、愤怒（10.20±3.32）、孤独（10.86±3.81）和抑郁（14.13±4.24）的得分显著高于封锁前焦虑（16.63±4.64）、愤怒（9.74±2.60）、孤独（10.26±3.35）和抑郁（13.11±4.24）的得分。这些差异具有统计学意义（<0.001）。
在COVID-19封锁期间，与封锁前相比，维持性血液透析患者的焦虑、愤怒、孤独和抑郁水平显著更高。我们的研究强调了在此类公共卫生危机期间充分关注血液透析患者心理健康的重要性。
