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美国高致病性H5N1禽流感:近期的传入及向牛群的传播

Highly pathogenic avian influenza H5N1 in the United States: recent incursions and spillover to cattle.

作者信息

Mostafa Ahmed, Nogales Aitor, Martinez-Sobrido Luis

机构信息

Host-pathogen interactions (HPI) and Disease Intervention and Prevention (DIP) programs, Texas Biomedical Research Institute, San Antonio, TX, USA.

Center of Scientific Excellence for Influenza Viruses, National Research Centre, Giza, Egypt.

出版信息

Npj Viruses. 2025 Jul 5;3(1):54. doi: 10.1038/s44298-025-00138-5.

Abstract

Since Spring 2024, new genotypes of highly pathogenic avian influenza (HPAI) H5N1 clade 2.3.4.4b have been identified in the United States (US). These HPAI H5N1 genotypes have caused unprecedented multi-state outbreaks in poultry and dairy farms, and human infections. Here, we discuss the current situation of this outbreak and emphasizes the need for pre-pandemic preparedness to control HPAI H5N1 in both poultry and dairy farms in the US.

摘要

自2024年春季以来,美国已发现高致病性禽流感(HPAI)H5N1进化分支2.3.4.4b的新基因型。这些HPAI H5N1基因型已在家禽和奶牛场引发了前所未有的多州疫情,并导致了人类感染。在此,我们讨论此次疫情的现状,并强调在美国的家禽和奶牛场防控HPAI H5N1进行大流行前准备的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a87/12228781/43c3ddd825ac/44298_2025_138_Fig1_HTML.jpg

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