Jagtap Swati, Altinli Mine, Badusche Marlis, Chevalier Manuel, Becker Norbert, Leggewie Mayke, Schnettler Esther
Bernhard-Nocht Institute for Tropical Medicine,Hamburg, Germany.
German Centre for Infection Research (DZIF), Partner Site Hamburg-Luebeck-Borstel-Riems, Germany.
One Health. 2025 May 4;20:101062. doi: 10.1016/j.onehlt.2025.101062. eCollection 2025 Jun.
O'nyong-nyong virus (ONNV) is a zoonotic vector-borne alphavirus with humans as primary hosts during urban outbreaks. While its enzootic transmission cycle is not well investigated, its pattern of disappearance and reemergence suggests overlooked but critical wildlife reservoirs. While ONNV travel-related cases were reported in Canada and Germany, autochthonous transmission is limited to sub-Saharan Africa. The lack of specialised vectors, such as anopheline mosquitoes, is considered to be one of the reasons. Here, we investigated the vector competence of native and invasive culicine mosquitoes from Germany. While the tested native culicine mosquitoes from Germany did not transmit ONNV, our results provide experimental evidence for potential ONNV transmission by invasive mosquitoes. We further investigated the role of temperature on ONNV transmission. mosquitoes are highly invasive and have become widespread in Europe in the last decade. Our results highlight that, combined with rising summer temperatures and the abundance of competent vectors, ONNV may emerge as a public health threat for Europe in the near future.
奥尼永-尼永病毒（ONNV）是一种人畜共患的媒介传播甲病毒，在城市疫情爆发期间，人类是其主要宿主。虽然其动物传播循环尚未得到充分研究，但其消失和重新出现的模式表明存在被忽视但至关重要的野生动物宿主。虽然在加拿大和德国报告了与ONNV旅行相关的病例，但本土传播仅限于撒哈拉以南非洲。缺乏专门的媒介，如按蚊，被认为是原因之一。在此，我们研究了来自德国的本土和入侵库蚊的媒介能力。虽然测试的来自德国的本土库蚊没有传播ONNV，但我们的结果为入侵蚊子潜在传播ONNV提供了实验证据。我们进一步研究了温度对ONNV传播的作用。蚊子具有高度入侵性，在过去十年中已在欧洲广泛传播。我们的结果强调，结合夏季气温上升和易感媒介数量增加，ONNV在不久的将来可能成为欧洲的公共卫生威胁。
