有证据表明，c-myc表达可定义两种基因上不同的结直肠癌形式。 - Suppr

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超能文献

Evidence that c-myc expression defines two genetically distinct forms of colorectal adenocarcinoma.

作者信息

Rothberg P G, Spandorfer J M, Erisman M D, Staroscik R N, Sears H F, Petersen R O, Astrin S M

出版信息

Br J Cancer. 1985 Oct;52(4):629-32. doi: 10.1038/bjc.1985.237.

DOI:10.1038/bjc.1985.237

PMID:4063140

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1977258/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63f1/1977258/4943aeb6e317/brjcancer00096-0141-a.jpg

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本文引用的文献

Mouse c-myc oncogene is located on chromosome 15 and translocated to chromosome 12 in plasmacytomas.小鼠c-myc癌基因位于15号染色体上，在浆细胞瘤中易位至12号染色体。

Science. 1982 Dec 24;218(4579):1319-21. doi: 10.1126/science.7146913.

Onc gene amplification in promyelocytic leukaemia cell line HL-60 and primary leukaemic cells of the same patient.早幼粒细胞白血病细胞系HL-60及同一患者原代白血病细胞中的癌基因扩增。

Nature. 1982 Sep 2;299(5878):61-3. doi: 10.1038/299061a0.

Novel myc oncogene RNA from abortive immunoglobulin-gene recombination in mouse plasmacytomas.来自小鼠浆细胞瘤中流产性免疫球蛋白基因重排的新型myc癌基因RNA

Cell. 1982 Dec;31(2 Pt 1):443-52. doi: 10.1016/0092-8674(82)90137-4.

Translocation of the c-myc gene into the immunoglobulin heavy chain locus in human Burkitt lymphoma and murine plasmacytoma cells.在人类伯基特淋巴瘤和鼠浆细胞瘤细胞中，c-myc基因易位至免疫球蛋白重链基因座。

Proc Natl Acad Sci U S A. 1982 Dec;79(24):7837-41. doi: 10.1073/pnas.79.24.7837.

Rat c-myc oncogene is located on chromosome 7 and rearranges in immunocytomas with t(6:7) chromosomal translocation.大鼠c-myc癌基因位于7号染色体上，并在伴有t(6;7)染色体易位的免疫细胞瘤中发生重排。

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Increased expression of myc-related oncogene mRNA characterizes most BALB/c plasmacytomas induced by pristane or Abelson murine leukemia virus.在大多数由 pristane 或 Abelson 鼠白血病病毒诱导的 BALB/c 浆细胞瘤中，与 myc 相关的癌基因 mRNA 表达增加是其特征。

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Homogeneously staining chromosomal regions contain amplified copies of an abundantly expressed cellular oncogene (c-myc) in malignant neuroendocrine cells from a human colon carcinoma.均匀染色的染色体区域包含来自人类结肠癌的恶性神经内分泌细胞中一个大量表达的细胞癌基因（c-myc）的扩增拷贝。

Proc Natl Acad Sci U S A. 1983 Mar;80(6):1707-11. doi: 10.1073/pnas.80.6.1707.

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