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全球炎症性肠病:新时代的机遇与挑战

Global Inflammatory Bowel Disease: Opportunities and Challenges for a New Era.

作者信息

Catalan-Serra Ignacio, Sebastian Shaji

机构信息

Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway.

Gastroenterology, Department of Medicine, Levanger Hospital, Nord-Trøndelag Hospital Trust, Levanger, Norway.

出版信息

United European Gastroenterol J. 2025 Oct;13(8):1410-1417. doi: 10.1002/ueg2.70075. Epub 2025 Jul 9.

DOI:10.1002/ueg2.70075
PMID:40632013
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12528997/
Abstract

Inflammatory Bowel Disease (IBD) has become a global disease. The increasing incidence of inflammatory bowel disease across the world is challenging the traditional view of IBD as a western disease and represents a unique opportunity to gain an understanding of the disease in diverse ethnic groups and in different socio-economical and geographical environments. However, the continued growth in prevalence in developing countries in the coming years will lead to increased use of health-care resources due to IBD-related complications, costs of drugs and indirect health costs. Here we analyze the challenges and opportunities that this situation represents and suggest actions and potential solutions to improve the quality of IBD care globally.

摘要

炎症性肠病(IBD)已成为一种全球性疾病。全球范围内炎症性肠病发病率的不断上升正在挑战将IBD视为西方疾病的传统观念,并为在不同种族群体以及不同社会经济和地理环境中了解该疾病提供了独特机会。然而,未来几年发展中国家患病率的持续增长将因IBD相关并发症、药物成本和间接医疗成本导致医疗资源使用增加。在此,我们分析这种情况所带来的挑战和机遇,并提出提高全球IBD护理质量的行动和潜在解决方案。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f4d/12528997/ca5f7e8d905f/UEG2-13-1410-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f4d/12528997/bd59e9bd45fa/UEG2-13-1410-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f4d/12528997/ca5f7e8d905f/UEG2-13-1410-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f4d/12528997/bd59e9bd45fa/UEG2-13-1410-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f4d/12528997/ca5f7e8d905f/UEG2-13-1410-g002.jpg

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本文引用的文献

1
Disproportionately Increasing Incidence of Inflammatory Bowel Disease in Female Patients and the Elderly: An Update Analysis from the Global Burden of Disease Study 2021.女性患者和老年人中炎症性肠病发病率的不成比例上升:来自2021年全球疾病负担研究的最新分析
Am J Gastroenterol. 2025 Mar 1;120(3):675-680. doi: 10.14309/ajg.0000000000003143. Epub 2024 Oct 18.
2
The Cost of Inflammatory Bowel Disease Care: How to Make it Sustainable.炎症性肠病护理的成本:如何使其可持续发展。
Clin Gastroenterol Hepatol. 2025 Feb;23(3):386-395. doi: 10.1016/j.cgh.2024.06.049. Epub 2024 Aug 14.
3
Challenges in the diagnosis and treatment of inflammatory bowel disease in Latin America.
拉丁美洲炎症性肠病诊断与治疗中的挑战
Lancet Gastroenterol Hepatol. 2024 Mar;9(3):263-272. doi: 10.1016/S2468-1253(23)00284-4.
4
Promoting equity in inflammatory bowel disease: a global approach to care.促进炎症性肠病的公平性:全球护理方法。
Lancet Gastroenterol Hepatol. 2024 Mar;9(3):192-194. doi: 10.1016/S2468-1253(23)00368-0. Epub 2024 Jan 11.
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Diet and Nutrition in Inflammatory Bowel Disease: A Review of the Literature.炎症性肠病中的饮食与营养:文献综述
Crohns Colitis 360. 2023 Dec 9;6(1):otad077. doi: 10.1093/crocol/otad077. eCollection 2024 Jan.
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Representation and reporting of diverse groups in randomised controlled trials of pharmacological agents in inflammatory bowel disease: a systematic review.炎症性肠病中药物随机对照试验中不同群体的代表性和报告情况:一项系统评价
Lancet Gastroenterol Hepatol. 2023 Dec;8(12):1143-1151. doi: 10.1016/S2468-1253(23)00193-0. Epub 2023 Oct 10.
9
Incidence and prevalence of inflammatory bowel diseases in a population from Buenos Aires, Argentina.阿根廷布宜诺斯艾利斯地区人群中炎症性肠病的发病率和流行率。
Gastroenterol Hepatol. 2024 Oct;47(8):804-812. doi: 10.1016/j.gastrohep.2023.09.012. Epub 2023 Oct 6.
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Trends of inflammatory bowel disease from the Global Burden of Disease Study (1990-2019).全球疾病负担研究(1990 - 2019年)中炎症性肠病的趋势
Indian J Gastroenterol. 2024 Feb;43(1):188-198. doi: 10.1007/s12664-023-01430-z. Epub 2023 Oct 3.