Anderson Neil
Department of Pathology, Case Western Reserve School of Medicine, Cleveland, Ohio, USA.
J Clin Microbiol. 2025 Aug 13;63(8):e0064425. doi: 10.1128/jcm.00644-25. Epub 2025 Jul 11.
In the manuscript entitled "Hematology Thin Smears Perform Equally to Parasitology Thick and Thin Blood Smears for the Diagnosis of and in a Low-Prevalence Setting," the investigators demonstrate that traditional hematology smears (HS) review can have comparable performance to formal blood parasite smears (PS) review. The authors quote a 93.3% sensitivity in comparison to thick smears. This increases to 100% considering only new diagnoses. The implications are that HS can be utilized as a practical and rapid alternative to PS. For clinical laboratories that are limited to only HS capabilities, these findings suggest that they may be able to be less reliant on reference laboratory PS testing, allowing for more rapid diagnosis and management. Even in clinical laboratories that offer both tests, the findings suggest a reassessment of how both HS and PS fit into the diagnostic process for blood parasites. Familiarity with the pros and cons of both approaches allows them to be employed in a way that maximizes patient care impact.
在题为《在低流行环境中，血液学薄涂片在诊断[疾病名称1]和[疾病名称2]方面与寄生虫学厚血膜和薄血膜表现相当》的手稿中，研究人员表明，传统血液学涂片（HS）检查与正式血液寄生虫涂片（PS）检查具有相当的性能。作者引用与厚涂片相比93.3%的灵敏度。仅考虑新诊断时，这一比例增至100%。这意味着HS可作为PS的一种实用且快速的替代方法。对于仅具备HS检测能力的临床实验室，这些发现表明它们可能能够减少对参考实验室PS检测的依赖，从而实现更快速的诊断和管理。即使在同时提供两种检测的临床实验室中，这些发现也表明需要重新评估HS和PS在血液寄生虫诊断过程中的作用。熟悉两种方法的优缺点可使它们以最大限度影响患者护理的方式得到应用。
