Effects of magnesium concentration on the regulation of nutrition and inflammation in nutritional support for cancer patients.

OBJECTIVES

Magnesium plays a crucial role in metabolic homeostasis and energy balance. This study aims to evaluate the effect of magnesium in regulating nutritional status and inflammatory responses in nutritional support.

METHODS

A survey of 86 lung cancer patients was conducted. The oral nutrition supplement group was given an oral nutritional solution that was magnesium-rich on the basis of the routine diet in the hospital, while a routine hospital diet was given to the control group. Changes in magnesium concentration, nutritional status, and inflammatory indicators were compared between groups.

RESULTS

There was no significant difference in the indicators on 1st day and 10th day compared to the control group (P > .05). However, the levels of Mg, ALB, PA, Hb, and TLC in the oral nutrition supplement group were significantly increased, and the levels of TNF-α, IL-6, and CRP were significantly reduced on the 21st day (P < .05).

CONCLUSIONS

Changes in magnesium concentration can improve nutritional status and inflammatory response. The synergistic effect of magnesium concentration and nutritional support may open a new avenue for the prevention and treatment of cancer patients.