• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

公众对高成本抗癌药物的认知及其对报销决策的影响。

Public perceptions of high-cost cancer drugs and the implications for reimbursement decisions.

作者信息

Noh Youran, Son Kyung-Bok

机构信息

College of Pharmacy, Hanyang University, 55 Hanyangdeahak-ro, Sangnok-gu, Ansan, Gyeonggi-do, 15588, South Korea.

出版信息

Health Econ Rev. 2025 Jul 12;15(1):61. doi: 10.1186/s13561-025-00659-y.

DOI:10.1186/s13561-025-00659-y
PMID:40646427
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12255032/
Abstract

BACKGROUND

Reimbursing high-cost cancer drugs presents challenges in managing uncertainty, setting appropriate prices, and controlling pharmaceutical expenditures. We examined the perspectives of the South Korean public on high-cost cancer drugs and policy options to improve reimbursement for these treatments.

METHODS

We conducted a self-rated, web-based survey from November to December 2023. We used a quota sampling method based on South Korean census data to recruit study participants. The questionnaire comprised four sections: socio-demographics, definitions of high-cost cancer drugs and reasons for their reimbursement, uncertainties associated with high-cost cancer drugs, and policy options to improve reimbursement for these treatments.

RESULTS

Of the 11,974 invitations sent, 1,000 participants completed the survey, resulting in a response rate of 8.35%. Three-quarters of the respondents agreed or strongly agreed that high-cost cancer drugs should be reimbursed. More than 70% accepted the need for price negotiations, even if they lead to drug withdrawals or delays in reimbursement decisions. A similar proportion agreed that new policy options, such as dual pricing and additional funding, should be introduced with caution.

CONCLUSION

The South Korean public perceives the reimbursement of high-cost cancer drugs as both a human rights measure and a government responsibility. However, they support reimbursement only when they are confident that the drug is safe, effective, and cost-effective.

摘要

背景

报销高成本癌症药物在应对不确定性、设定合理价格以及控制药品支出方面存在挑战。我们研究了韩国公众对高成本癌症药物的看法以及改善这些治疗报销情况的政策选择。

方法

我们在2023年11月至12月进行了一项基于网络的自评调查。我们采用基于韩国人口普查数据的配额抽样方法招募研究参与者。问卷包括四个部分:社会人口统计学、高成本癌症药物的定义及其报销原因、与高成本癌症药物相关的不确定性,以及改善这些治疗报销情况的政策选择。

结果

在发出的11974份邀请中,有1000名参与者完成了调查,回复率为8.35%。四分之三的受访者同意或强烈同意高成本癌症药物应予以报销。超过70%的人接受价格谈判的必要性,即使这会导致药物撤市或报销决定延迟。类似比例的人同意应谨慎引入双重定价和额外资金等新政策选择。

结论

韩国公众认为报销高成本癌症药物既是一项人权措施,也是政府的责任。然而,只有当他们确信药物安全、有效且具有成本效益时,才会支持报销。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d1ab/12255032/4bf034e11cf4/13561_2025_659_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d1ab/12255032/f1837581b87e/13561_2025_659_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d1ab/12255032/b67ff49594a8/13561_2025_659_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d1ab/12255032/4bf034e11cf4/13561_2025_659_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d1ab/12255032/f1837581b87e/13561_2025_659_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d1ab/12255032/b67ff49594a8/13561_2025_659_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d1ab/12255032/4bf034e11cf4/13561_2025_659_Fig3_HTML.jpg

相似文献

1
Public perceptions of high-cost cancer drugs and the implications for reimbursement decisions.公众对高成本抗癌药物的认知及其对报销决策的影响。
Health Econ Rev. 2025 Jul 12;15(1):61. doi: 10.1186/s13561-025-00659-y.
2
A rapid and systematic review of the clinical effectiveness and cost-effectiveness of paclitaxel, docetaxel, gemcitabine and vinorelbine in non-small-cell lung cancer.对紫杉醇、多西他赛、吉西他滨和长春瑞滨在非小细胞肺癌中的临床疗效和成本效益进行的快速系统评价。
Health Technol Assess. 2001;5(32):1-195. doi: 10.3310/hta5320.
3
Sexual Harassment and Prevention Training性骚扰与预防培训
4
Systemic treatments for metastatic cutaneous melanoma.转移性皮肤黑色素瘤的全身治疗
Cochrane Database Syst Rev. 2018 Feb 6;2(2):CD011123. doi: 10.1002/14651858.CD011123.pub2.
5
Home treatment for mental health problems: a systematic review.心理健康问题的居家治疗:一项系统综述
Health Technol Assess. 2001;5(15):1-139. doi: 10.3310/hta5150.
6
A rapid and systematic review of the clinical effectiveness and cost-effectiveness of topotecan for ovarian cancer.拓扑替康治疗卵巢癌的临床有效性和成本效益的快速系统评价。
Health Technol Assess. 2001;5(28):1-110. doi: 10.3310/hta5280.
7
Behavioral interventions to reduce risk for sexual transmission of HIV among men who have sex with men.降低男男性行为者中艾滋病毒性传播风险的行为干预措施。
Cochrane Database Syst Rev. 2008 Jul 16(3):CD001230. doi: 10.1002/14651858.CD001230.pub2.
8
Topotecan, pegylated liposomal doxorubicin hydrochloride and paclitaxel for second-line or subsequent treatment of advanced ovarian cancer: a systematic review and economic evaluation.拓扑替康、聚乙二醇化脂质体盐酸多柔比星和紫杉醇用于晚期卵巢癌二线或后续治疗:一项系统评价和经济学评估
Health Technol Assess. 2006 Mar;10(9):1-132. iii-iv. doi: 10.3310/hta10090.
9
Signs and symptoms to determine if a patient presenting in primary care or hospital outpatient settings has COVID-19.在基层医疗机构或医院门诊环境中,如果患者出现以下症状和体征,可判断其是否患有 COVID-19。
Cochrane Database Syst Rev. 2022 May 20;5(5):CD013665. doi: 10.1002/14651858.CD013665.pub3.
10
Pharmaceutical policies: effects of financial incentives for prescribers.药品政策:针对开处方者的经济激励措施的影响。
Cochrane Database Syst Rev. 2015 Aug 4;2015(8):CD006731. doi: 10.1002/14651858.CD006731.pub2.

本文引用的文献

1
Analysis of drug pricing drivers under South Korea's pharmaco-economic evaluation exemption policy (2015-2022).韩国药物经济学评估豁免政策(2015 - 2022年)下的药品定价驱动因素分析
Front Pharmacol. 2025 Jan 7;15:1519491. doi: 10.3389/fphar.2024.1519491. eCollection 2024.
2
Preferences for speed of access versus certainty of the survival benefit of new cancer drugs: a discrete choice experiment.对新癌症药物获取速度与生存获益确定性的偏好:一项离散选择实验
Lancet Oncol. 2024 Dec;25(12):1635-1643. doi: 10.1016/S1470-2045(24)00596-5. Epub 2024 Nov 18.
3
Perceptions of risk sharing agreements in South Korea from the viewpoints of key stakeholders: a convergent parallel mixed approach.
从关键利益相关者的视角看韩国风险分担协议的认知:一种收敛平行混合方法。
Expert Rev Pharmacoecon Outcomes Res. 2025 Feb;25(2):235-243. doi: 10.1080/14737167.2024.2410250. Epub 2024 Sep 30.
4
Public value judgments about the criteria for reimbursement of medicines in South Korea.韩国关于药品报销标准的公共价值判断。
Expert Rev Pharmacoecon Outcomes Res. 2025 Jan;25(1):53-61. doi: 10.1080/14737167.2024.2388815. Epub 2024 Aug 6.
5
Special FDA designations for drug development: orphan, fast track, accelerated approval, priority review, and breakthrough therapy.药物研发的特殊 FDA 认定:孤儿药、快速通道、加速批准、优先审评和突破性疗法。
Eur J Health Econ. 2024 Aug;25(6):979-997. doi: 10.1007/s10198-023-01639-x. Epub 2023 Nov 14.
6
Cancer Drugs Reimbursed with Limited Evidence on Overall Survival and Quality of Life: Do Follow-Up Studies Confirm Patient Benefits?癌症药物在总生存和生活质量方面的证据有限得到报销:后续研究是否确认了患者获益?
Clin Drug Investig. 2023 Aug;43(8):621-633. doi: 10.1007/s40261-023-01285-4. Epub 2023 Jul 28.
7
Regulatory benefit-risk assessment of oncology drugs: A systematic review of FDA and EMA approvals.肿瘤药物的监管获益-风险评估:FDA 和 EMA 批准的系统评价。
Drug Discov Today. 2023 Oct;28(10):103719. doi: 10.1016/j.drudis.2023.103719. Epub 2023 Jul 17.
8
High Cost of Chimeric Antigen Receptor T-Cells: Challenges and Solutions.嵌合抗原受体 T 细胞治疗费用高昂:挑战与对策。
Am Soc Clin Oncol Educ Book. 2023 Jun;43:e397912. doi: 10.1200/EDBK_397912.
9
Tackling reimbursement challenges to fair access to medicines - introduction to the topic.解决公平获得药物的报销挑战 - 主题介绍。
Expert Rev Pharmacoecon Outcomes Res. 2023 Jul-Dec;23(6):597-606. doi: 10.1080/14737167.2023.2203384. Epub 2023 Apr 17.
10
Cancer Therapy Approval Timings, Review Speed, and Publication of Pivotal Registration Trials in the US and Europe, 2010-2019.2010-2019 年美国和欧洲的癌症治疗审批时间、审查速度和关键注册试验的发表情况。
JAMA Netw Open. 2022 Jun 1;5(6):e2216183. doi: 10.1001/jamanetworkopen.2022.16183.