Tsurugizawa Tomokazu, Komaki Yuji, Aota Illia, Suematsu Makoto, Ohtaka-Maruyama Chiaki, Kumamoto Takuma
National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Ibaraki, Japan.
Institute of Systems and Information Engineering, University of Tsukuba, Tsukuba, Ibaraki, Japan.
Sci Data. 2025 Jul 12;12(1):1206. doi: 10.1038/s41597-025-05540-5.
Understanding brain evolution requires detailed comparative analyses of brain structures across species. However, high-resolution anatomical and connective data remain limited for most vertebrates beyond a few well-studied model organisms. To address this gap, we collected postmortem brain samples from a range of vertebrates, primarily small amniotes, and performed magnetic resonance imaging and histological staining. Here, we present the "Animal Brain Collection (ABC)," a freely accessible database that enables researchers to examine and compare cellular and tissue-level brain architectures across species. This resource provides a foundation for cross-species investigations of brain structure and development, offering new opportunities for research into the diversity and evolution of vertebrate brains.
了解大脑进化需要对跨物种的大脑结构进行详细的比较分析。然而，除了少数经过充分研究的模式生物外，大多数脊椎动物的高分辨率解剖学和连接数据仍然有限。为了填补这一空白，我们收集了一系列脊椎动物（主要是小型羊膜动物）的死后大脑样本，并进行了磁共振成像和组织学染色。在这里，我们展示了“动物大脑集合（ABC）”，这是一个可免费访问的数据库，使研究人员能够检查和比较跨物种的细胞和组织水平的脑结构。该资源为大脑结构和发育的跨物种研究提供了基础，为脊椎动物大脑的多样性和进化研究提供了新的机会。
