Chhabra Ajay, Mehra Himani, Yadav Priyanka, Ramya K P, Prathap Saravana B, Sengupta Mallika, Parvathy Sona J, Chhabra Vandana
Department of Dentistry, AIIMS Kalyani, Kalyani, West Bengal, India.
Department of Microbiology, AIIMS Kalyani, Kalyani, West Bengal, India.
J Pharm Bioallied Sci. 2025 Jun;17(Suppl 2):S1908-S1910. doi: 10.4103/jpbs.jpbs_186_25. Epub 2025 Jun 18.
To evaluate the antimicrobial efficacy of different irrigants combined with silver nanoparticles.
Thirty-five patients were divided into seven groups (two control and five experimental), including Group 1: negative control (normal saline), Group 2: positive control (sodium hypochlorite), and Group 3 (sodium hypochlorite + AgNP), Group 4 (Twin Kleen), Group 5 (Twin Kleen + AgNP), Group 6 (Q Mix), and Group 7 (Q Mix + AgNP). Pre- and post-treatment bacterial samples were collected for analysis.
Sodium hypochlorite combined with silver nanoparticles demonstrated the highest antimicrobial efficacy among the tested irrigants, with a significant difference confirmed by the Chi-square statistical analysis.
Within the limitations of the study, it can be concluded that sodium hypochlorite when mixed with the silver nanoparticles showed higher antimicrobial efficacy as compared to the other tested groups.
评估不同冲洗剂与银纳米颗粒联合使用时的抗菌效果。
35例患者被分为7组（2个对照组和5个试验组），包括第1组：阴性对照组（生理盐水），第2组：阳性对照组（次氯酸钠），以及第3组（次氯酸钠 + 银纳米颗粒），第4组（Twin Kleen），第5组（Twin Kleen + 银纳米颗粒），第6组（Q Mix），和第7组（Q Mix + 银纳米颗粒）。收集治疗前和治疗后的细菌样本进行分析。
在测试的冲洗剂中，次氯酸钠与银纳米颗粒联合使用显示出最高的抗菌效果，卡方统计分析证实了显著差异。
在本研究的局限性范围内，可以得出结论，与其他测试组相比，次氯酸钠与银纳米颗粒混合时显示出更高的抗菌效果。
