O'Toole Nina, Allen Matthew E, Contini Claudia, Elani Yuval
Department of Chemical Engineering, Imperial College London, South Kensington, London SW7 2AZ, UK.
Institute of Chemical Biology, Imperial College London, Molecular Sciences Research Hub, London, W12 0BZ, UK.
Chem Commun (Camb). 2025 Jul 14. doi: 10.1039/d5cc00449g.
Bacterial biohybrids use bacterial and synthetic components for biotechnological applications. Here, we outline an adaptable and high-throughput microfluidic platform to create microscale biocontained bacterial biohybrids enclosed in a hydrogel with magnetotactic and biosensing properties. The biohybrids are capable of magnetically driven motility, biochemical sensing and controlled cargo release. This approach enables the scalable fabrication of biocontained multifunctional biohybrids for potential industrial and biomedical applications.
细菌生物杂交体利用细菌和合成成分用于生物技术应用。在此，我们概述了一种适应性强且高通量的微流控平台，用于创建包裹在具有趋磁和生物传感特性的水凝胶中的微型生物包含细菌生物杂交体。这些生物杂交体能够进行磁驱动运动、生化传感和可控的货物释放。这种方法能够可扩展地制造用于潜在工业和生物医学应用的生物包含多功能生物杂交体。
