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3D打印技术结合莫氏锥度与平台转换设计对牙种植体微渗漏性能的影响

The effect of 3D printing technology combined with Morse taper and platform switching design on microleakage performance of dental implants.

作者信息

Jing Yiwan, Wang Xue, Long Shuai, He Si, Xiong Nana, Dong Zhihong, Cheng Lijia, He Liuxing

机构信息

School of Basic Medical Sciences, Mechanical Engineering College, Chengdu University, Chengdu, 610106, China.

出版信息

Odontology. 2025 Jul 14. doi: 10.1007/s10266-025-01152-y.

Abstract

This study aims to investigate the effects of a Morse taper connection combined with platform switching design and hydroxyapatite (HA) coating on the mechanical properties, bacterial leakage, bioactivity, and osteogenic properties of dental implants. Four groups of models (platform switching of 0 and 0.6 mm; Morse taper of 0° and 10°) were determined through three-dimensional finite element analysis and labeled as TI, P, T, and PT groups. The dental implants were fabricated using selective laser melting and then surface-modified with sandblasting, acid etching, and HA coating. The physicochemical properties of the implants were measured using scanning electron microscopy (SEM), X-ray diffraction (XRD), energy dispersive spectrometry (EDS), and profilometry. Bacterial leakage was detected by colony counting. Finally, the biocompatibility, bioactivity, and osteogenic capacity of the implants were assessed through cell culture, immunohistochemistry, and Western blot. Significant differences were observed between the PT and Ti groups in terms of morphology, mechanical properties, and bacterial leakage. HA coating significantly enhanced the bioactivity of the implants. Implants modified by sandblasting, acid etching, and HA coating exhibited better biocompatibility, bioactivity, and osteogenic capacity compared to unmodified implants. Additionally, the PT group showed a significant improvement in reducing bacterial leakage. The Morse taper connection combined with platform switching design places less stress on the implant system than conventional platform-docked implants. The narrowing of the abutment neck is more favorable for the attachment of osteoblast-associated cells.

摘要

本研究旨在探讨莫氏锥度连接结合平台转换设计及羟基磷灰石(HA)涂层对牙种植体力学性能、细菌渗漏、生物活性和成骨性能的影响。通过三维有限元分析确定了四组模型(平台转换分别为0和0.6毫米;莫氏锥度分别为0°和10°),并标记为TI、P、T和PT组。采用选择性激光熔化制造牙种植体,然后通过喷砂、酸蚀和HA涂层进行表面改性。使用扫描电子显微镜(SEM)、X射线衍射(XRD)、能量色散光谱(EDS)和轮廓仪测量种植体的物理化学性质。通过菌落计数检测细菌渗漏。最后,通过细胞培养、免疫组织化学和蛋白质印迹评估种植体的生物相容性、生物活性和成骨能力。在形态、力学性能和细菌渗漏方面,PT组和Ti组之间观察到显著差异。HA涂层显著增强了种植体的生物活性。与未改性的种植体相比,经喷砂、酸蚀和HA涂层改性的种植体表现出更好的生物相容性、生物活性和成骨能力。此外,PT组在减少细菌渗漏方面有显著改善。与传统平台对接种植体相比,莫氏锥度连接结合平台转换设计对种植体系统施加的应力更小。基台颈部变窄更有利于成骨细胞相关细胞的附着。

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