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身心医学:中枢神经系统通过与组织、器官和细胞的连接进行的沟通。

Psychosomatics: Communication of the Central Nervous System through Connection to Tissues, Organs, and Cells.

作者信息

Efremov Andrei

机构信息

Mind Networks Association LLC, Wilmington, NC, USA.

出版信息

Clin Psychopharmacol Neurosci. 2024 Nov 30;22(4):565-577. doi: 10.9758/cpn.24.1197. Epub 2024 Sep 6.

DOI:10.9758/cpn.24.1197
PMID:39420604
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11494424/
Abstract

This study aimed to scrutinize existing evidence concerning the link between somatic symptoms and nervous system activity. The goal was to pinpoint areas for effective therapeutic interventions. Psychosomatic disorders, an often overlooked field of medicine, bears significance given the multitude of patients experiencing somatic symptoms due to specific emotions and experiences. The literature was explored using the methods of comparative analysis, synthesis and graphical representation. The study introduced pathological neural networks localized in brain regions such as the prefrontal cortex and hippocampus, leading to maladaptive behaviors and heightened negative focus. Activation of the sympathetic nervous system and the hypothalamus-pituitary-adrenal axis, alongside increased cortisol levels, induces chronic distress, inflammation, and disruptions in neurotransmitter metabolism. The gut microbiota significantly influences psychosomatic reactions. Patients with psychosomatic disorders require complex treatment with cognitive-behavioural therapy and hypnosis methods. Within the framework of pathological neural networks, the MindChat technique has yielded effectiveness with the purpose of "dehypnotization" and destruction of aberrant cognitive and emotional patterns. However, it should be noted that this technique requires further empirical support.

摘要

本研究旨在审视关于躯体症状与神经系统活动之间联系的现有证据。目标是确定有效的治疗干预领域。心身疾病是医学中一个常被忽视的领域,鉴于众多患者因特定情绪和经历而出现躯体症状,它具有重要意义。采用比较分析、综合和图形表示的方法对文献进行了探索。该研究介绍了位于前额叶皮层和海马体等脑区的病理性神经网络,这些网络会导致适应不良行为和负面关注点增加。交感神经系统和下丘脑 - 垂体 - 肾上腺轴的激活,以及皮质醇水平的升高,会引发慢性应激、炎症和神经递质代谢紊乱。肠道微生物群对心身反应有显著影响。心身疾病患者需要采用认知行为疗法和催眠方法进行综合治疗。在病理性神经网络的框架内,MindChat技术在“解除催眠”和破坏异常认知及情绪模式方面已取得成效。然而,应当指出的是,该技术需要进一步的实证支持。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f2cf/11494424/a7cabc1a267b/cpn-22-4-565-f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f2cf/11494424/925278594b2c/cpn-22-4-565-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f2cf/11494424/8d7288ad7ee7/cpn-22-4-565-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f2cf/11494424/a7cabc1a267b/cpn-22-4-565-f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f2cf/11494424/925278594b2c/cpn-22-4-565-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f2cf/11494424/8d7288ad7ee7/cpn-22-4-565-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f2cf/11494424/a7cabc1a267b/cpn-22-4-565-f3.jpg

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