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青少年和青年腰痛的负担变化、风险因素及预测:来自《2021年全球疾病负担研究》的见解

Changing Burden, Risk Factors, and Projections of Low Back Pain in Adolescents and Young Adults: Insights from the Global Burden of Disease Study 2021.

作者信息

Zhang Yanbin, Yang Chaoqun, Bai Jing, Xiao Bin, Zhang Jianguo, Sun Rongyin, He Da

机构信息

Department of Spine Surgery, Beijing Jishuitan Hospital, Capital Medical University, Beijing 100035, China.

Department of Spine Surgery, Jinan Third People's Hospital, Jinan 250132, China.

出版信息

Spine (Phila Pa 1976). 2025 Jul 14;50(19):1363-73. doi: 10.1097/BRS.0000000000005447.

Abstract

STUDY DESIGN

Ecological study.

OBJECTIVE

To illustrate the spatiotemporal trends, attributable risk factors, and the projected burden of LBP among adolescents and young adults (AYAs) aged 15-39 years.

SUMMARY OF BACKGROUND DATA

Low back pain (LBP) poses a considerable challenge to individuals and society, and current epidemiological trends in AYAs experiencing LBP remain to be explored.

METHODS

Data extracted from the Global Burden of Disease 2021 study were utilized to examine the LBP burden among AYAs on global, regional, and national scales between 1990 and 2021. This ecological study also investigated global age-sex differences and the percentage of the burden linked to risk elements, while employing the Bayesian age-period-cohort model to project worldwide trends until 2036.

RESULTS

Between 1990 and 2021, the worldwide counts of incident, prevalent, and years lived with disability (YLDs) cases of LBP in AYAs rose. The calculated estimated annual percentage changes and relevant 95% confidence intervals indicated decreasing trends in age-standardized incidence rate, age-standardized prevalence rate, and age-standardized YLDs rate throughout the study period. The highest counts of prevalent, incident, and YLDs cases were found in regions with middle SDI in 2021, whereas high SDI areas experienced the maximum age-standardized rates. Females carried a heavier burden compared with males on a global scale. Occupational ergonomic factors contributed to the most significant percentage of YLDs globally in 2021, accounting for 26.93%. Predictions for the period 2022-2036 suggested a decline in the age-standardized rates of females worldwide, while the burden of females was predicted to remain higher than that of males.

CONCLUSION

To tackle the current and possibly rising burden of LBP among AYAs, comprehensive and suitable interventions should be tailored to meet regional and sex disparities.

摘要

研究设计

生态学研究。

目的

阐明15 - 39岁青少年及青年(AYA)中腰痛(LBP)的时空趋势、可归因风险因素及预计负担。

背景数据总结

腰痛给个人和社会带来了巨大挑战,AYA中腰痛的当前流行病学趋势仍有待探索。

方法

利用从《2021年全球疾病负担》研究中提取的数据,在全球、区域和国家层面上研究1990年至2021年期间AYA的腰痛负担。这项生态学研究还调查了全球年龄 - 性别差异以及与风险因素相关的负担百分比,同时使用贝叶斯年龄 - 时期 - 队列模型预测到2036年的全球趋势。

结果

1990年至2021年期间,AYA中腰痛的新发、现患和伤残调整生命年(YLD)病例数在全球范围内有所增加。计算得出的估计年百分比变化及相关95%置信区间表明,在整个研究期间,年龄标准化发病率、年龄标准化患病率和年龄标准化YLD率呈下降趋势。2021年,中社会人口指数(SDI)地区的现患、新发和YLD病例数最多,而高SDI地区的年龄标准化率最高。在全球范围内,女性的负担比男性更重。2021年,职业工效学因素在全球YLD中所占比例最高,为26.93%。对2022 - 2036年期间的预测表明,全球女性的年龄标准化率将下降,而预计女性的负担仍将高于男性。

结论

为应对当前及可能上升的AYA腰痛负担,应制定全面且合适的干预措施,以满足地区和性别差异。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/58a4/12410083/ec4bebe09903/brs-50-1363-g001.jpg

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