Valdiserri E V
J Clin Psychiatry. 1985 Dec;46(12):540-1.
The calcium channel blockers are a group of drugs that have recently become available for the treatment of angina. They act by blocking the entry of calcium into cells during depolarization. Lithium has electrochemical qualities similar to calcium and influences calcium metabolism and calcium transport. The case reported here documents the use of diltiazem in a patient treated with lithium. A possible synergistic drug interaction occurring between diltiazem and lithium is reported.
钙通道阻滞剂是最近可用于治疗心绞痛的一类药物。它们通过在去极化过程中阻止钙进入细胞来发挥作用。锂具有与钙相似的电化学性质，并影响钙代谢和钙转运。本文报道的病例记录了地尔硫䓬在一名接受锂治疗的患者中的应用。据报道，地尔硫䓬与锂之间可能发生协同药物相互作用。
