分离的衣藻鞭毛中的α-微管蛋白乙酰化酶活性。
Alpha-tubulin acetylase activity in isolated Chlamydomonas flagella.
作者信息
Greer K, Maruta H, L'Hernault S W, Rosenbaum J L
出版信息
J Cell Biol. 1985 Dec;101(6):2081-4. doi: 10.1083/jcb.101.6.2081.
Abstract
We have previously shown that the alpha-tubulin of Chlamydomonas flagella is synthesized as a precursor which is modified by acetylation in the flagellum during flagellar assembly. In this report, we show the presence of an alpha-tubulin acetylase activity in isolated Chlamydomonas flagella that is highly specific for alpha-tubulin of both mammalian brain and Chlamydomonas.
摘要
我们之前已经表明，衣藻鞭毛的α-微管蛋白是以一种前体形式合成的，该前体在鞭毛组装过程中在鞭毛内通过乙酰化进行修饰。在本报告中，我们展示了在分离的衣藻鞭毛中存在一种α-微管蛋白乙酰转移酶活性，该活性对哺乳动物脑和衣藻的α-微管蛋白都具有高度特异性。
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