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绵羊肺炎支原体和精氨酸支原体在羊和山羊气管器官培养物中的致病性。

The pathogenicity of Mycoplasma ovipneumoniae and Mycoplasma arginini in ovine and caprine tracheal organ cultures.

作者信息

Jones G E, Keir W A, Gilmour J S

出版信息

J Comp Pathol. 1985 Oct;95(4):477-87. doi: 10.1016/0021-9975(85)90018-0.

DOI:10.1016/0021-9975(85)90018-0
PMID:4067018
Abstract

The effects of M. ovipneumoniae and M. arginini on tracheal organ cultures prepared from a neonatal kid and a foetal lamb were studied. Both organisms were isolated from the cultures throughout the 14 days of observation. M. ovipneumoniae produced ciliostasis and loss of cilia, confirmed by scanning electron microscope (SEM), after 4 days. These effects were sudden and profound in lamb explants, and gradual and less pronounced in kid explants. Clusters of organisms attached to epithelial surfaces and in association with cilia were visible by SEM. M. arginini also induced ciliostasis and cilia loss in both kid and lamb explants, but onset was more rapid, at 2 days, and there was evident recovery after day 6, with apparent regeneration of cilia. No clearly recognizable mycoplasmas were observed by SEM in M. arginini-infected explants.

摘要

研究了绵羊肺炎支原体和精氨酸支原体对新生山羊和胎羊制备的气管器官培养物的影响。在整个14天的观察期内,两种微生物均从培养物中分离出来。4天后,绵羊肺炎支原体导致纤毛运动停滞和纤毛丧失,扫描电子显微镜(SEM)证实了这一点。这些影响在羔羊外植体中是突然且显著的,而在山羊外植体中则是逐渐的且不太明显。通过扫描电子显微镜可见附着在上皮表面并与纤毛相关的微生物簇。精氨酸支原体在山羊和羔羊外植体中也诱导了纤毛运动停滞和纤毛丧失,但发病更快,在第2天,并且在第6天后有明显恢复,纤毛明显再生。在精氨酸支原体感染的外植体中,扫描电子显微镜未观察到明显可识别的支原体。

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