Zhang Yan, Zhou Jin, Han Lei, Jia Qiang, Du Lili, Li Jin, Li Wenjie, Zeng Qiang, Zhou Lifang, Kang Tongying, Gu Yiting, Cheng Xiurong, Xing Caihong
State Key Laboratory of Trauma and Chemical Poisoning, National Institute for Occupational Health and Poison Control, Chinese Center for Disease Control and Prevention, Beijing, China.
State Key Laboratory of Trauma, Burn and Combined Injury, Third Military Medical University, Chongqing, China.
China CDC Wkly. 2025 Jul 4;7(27):909-914. doi: 10.46234/ccdcw2025.152.
As a major producer and consumer of benzene, China has long confronted the challenge of occupational chronic benzene poisoning (OCBP). Between 2005 and 2019, OCBP in China primarily occurred in private enterprises, small- and medium-sized enterprises, and the general/special-purpose equipment manufacturing industry. However, with the continuous strengthening of national supervision and restrictions on the use of benzene-containing materials, the industrial distribution of OCBP may have changed from 2020 to 2023.
A total of 6 provincial-level administrative divisions (PLADs) with concentrated benzene-related industries - Jiangsu, Zhejiang, Shandong, Sichuan, Fujian, and Tianjin - were selected for analysis. We collected data on 162 newly reported OCBP cases from 2020 to 2023. Based on the National Economic Industry Classification standards, we analyzed these cases according to enterprise size, economic type, and industry classification.
The number of OCBP cases in China decreased significantly, reaching a historical low of 56 cases in 2023 [accounting for 15.3% of chronic occupational poisoning (COP)], compared to an average of 256 cases annually from 2005 to 2019 (26.7% of COP). From 2020 to 2023, OCBP continued to occur predominantly in manufacturing, private, and small- and medium-sized enterprises. However, the primary industry associated with OCBP shifted to chemical raw materials and chemical products manufacturing, followed by petroleum, coal, and other fuel processing industries.
OCBP remains a major component of COP in China. While continuing to regulate the manufacturing industry, especially small- and medium-sized enterprises, supervision should be strengthened in the evolving industries where benzene poisoning now predominantly occurs.
作为苯的主要生产国和消费国,中国长期面临职业性慢性苯中毒(OCBP)的挑战。2005年至2019年期间,中国的职业性慢性苯中毒主要发生在民营企业、中小企业以及通用/专用设备制造业。然而,随着国家对含苯材料使用监管和限制的不断加强,2020年至2023年职业性慢性苯中毒的行业分布可能已发生变化。
选取了6个苯相关产业集中的省级行政区——江苏、浙江、山东、四川、福建和天津进行分析。我们收集了2020年至2023年162例新报告的职业性慢性苯中毒病例的数据。根据《国民经济行业分类》标准,我们按企业规模、经济类型和行业分类对这些病例进行了分析。
中国职业性慢性苯中毒病例数显著下降,2023年降至历史最低点56例[占慢性职业中毒(COP)的15.3%],而2005年至2019年平均每年为256例(占慢性职业中毒的26.7%)。2020年至2023年,职业性慢性苯中毒仍主要发生在制造业、民营企业以及中小企业。然而,与职业性慢性苯中毒相关的主要行业已转向化学原料和化学制品制造业,其次是石油、煤炭及其他燃料加工业。
职业性慢性苯中毒仍是中国慢性职业中毒的主要组成部分。在继续规范制造业,特别是中小企业的同时,应加强对苯中毒目前主要发生的新兴行业的监管。