Mondoh Alvin, Craig Hilary, Crotty Michael, Contreras Francisca, le Roux Carel W
Diabetes Complications Research Centre, Conway Institute of Biomedical and Biomolecular Research, University College Dublin, Dublin 4, Ireland.
UCD School of Medicine, University College Dublin, Dublin 4, Ireland.
Obes Pillars. 2025 Jun 16;15:100187. doi: 10.1016/j.obpill.2025.100187. eCollection 2025 Sep.
The rising prevalence of obesity is of particular concern due to its association with a range of serious complications, including type 2 diabetes mellitus, cardiovascular diseases, and certain types of cancer. Obesity medications can control the disease but it is unclear how patients choose which medication to use.
A qualitative thematic analysis was conducted to investigate how patients select between obesity medications. Fifteen treatment naive adults with a body mass index ≥27 kg/m with at least one weight-related complications were recruited.
The 5 major themes depicting how patients make selections included 1) Effectiveness of medication, 2) Information to make decisions, 3) Safety of medications, 4) Practicality and 5) Individual Strategies and Community Supports in Obesity Management. Safety concerns of side effects and long-term risks were perceived major barriers to initiating or adhering to pharmacotherapy.
In a situation where the medications are described as being free and readily available, patient preferences for obesity medications are shaped by treatment efficacy, safety, information provided by healthcare providers. To enhance adherence and improve patient outcomes, healthcare providers should focus on delivering clear, comprehensive information and fostering strong support systems for patients.
肥胖症患病率的不断上升尤其令人担忧,因为它与一系列严重并发症相关,包括2型糖尿病、心血管疾病和某些类型的癌症。肥胖症药物可以控制这种疾病,但患者如何选择使用哪种药物尚不清楚。
进行了一项定性主题分析,以调查患者如何在肥胖症药物之间进行选择。招募了15名体重指数≥27kg/m²且至少有一种与体重相关并发症的初治成年人。
描述患者如何做出选择的5个主要主题包括:1)药物疗效,2)决策信息,3)药物安全性,4)实用性,以及5)肥胖管理中的个人策略和社区支持。对副作用和长期风险的安全担忧被认为是开始或坚持药物治疗的主要障碍。
在药物被描述为免费且容易获得的情况下,患者对肥胖症药物的偏好受治疗效果、安全性、医疗保健提供者提供的信息影响。为了提高依从性并改善患者预后,医疗保健提供者应专注于提供清晰、全面的信息,并为患者建立强大的支持系统。