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一例植入颈椎脊髓刺激器患者发生的退行性颈椎脊髓病:病例报告

Degenerative Cervical Myelopathy in a Patient With a Pre-existing Cervical Spinal Cord Stimulator: A Case Report.

作者信息

Walton Chase, Jenkins Sarah, Ferdon Robert J, Lawrence James, Ravinsky Robert

机构信息

Department of Orthopaedics and Physical Medicine, Medical University of South Carolina, Charleston, USA.

Department of Orthopaedic Surgery, University of South Carolina, Columbia, USA.

出版信息

Cureus. 2025 Jun 17;17(6):e86204. doi: 10.7759/cureus.86204. eCollection 2025 Jun.

DOI:10.7759/cureus.86204
PMID:40677429
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12270518/
Abstract

Degenerative cervical myelopathy (DCM) is a progressive condition that can lead to significant neurologic disability if not promptly diagnosed and treated. The presence of a neuromodulation device in the spinal canal, such as a spinal cord stimulator (SCS), can potentially hinder the diagnosis and management of DCM. Here, we report a case of a 53-year-old female patient with a history of complex regional pain syndrome being managed with a cervical SCS, who presented with DCM and rapid neurological deterioration and bilateral lower extremity paralysis. The diagnostic workup was rendered more challenging due to contraindications for MRI related to the implanted SCS. CT myelogram demonstrated multilevel cervical stenosis with cord compression; the cervical leads were believed to contribute to the central stenosis. The patient underwent anterior cervical discectomy and fusion (ACDF) from C4 to C7, resulting in immediate improvement in her motor function and an uncomplicated postoperative course. At discharge, she had regained full strength in the lower extremities. This case highlights the unique diagnostic and management challenges of DCM in patients with pre-existing cervical neuromodulation devices. A high index of suspicion and timely use of alternative imaging modalities were essential for achieving favorable outcomes in this complex patient. Further research is needed to establish evidence-based recommendations for the management of DCM in the setting of neuromodulation devices.

摘要

退行性颈椎脊髓病(DCM)是一种进行性疾病,如果不及时诊断和治疗,可导致严重的神经功能障碍。椎管内存在神经调节装置,如脊髓刺激器(SCS),可能会妨碍DCM的诊断和治疗。在此,我们报告一例53岁女性患者,有复杂区域疼痛综合征病史,正在接受颈椎SCS治疗,出现了DCM并伴有快速神经功能恶化和双侧下肢瘫痪。由于植入SCS导致MRI检查存在禁忌证,诊断性检查变得更具挑战性。CT脊髓造影显示多节段颈椎管狭窄伴脊髓受压;颈椎导联被认为是导致中央管狭窄的原因。患者接受了从C4到C7的颈椎前路椎间盘切除融合术(ACDF),术后运动功能立即改善,术后过程顺利。出院时,她下肢力量已完全恢复。该病例突出了在已有颈椎神经调节装置的患者中DCM独特的诊断和治疗挑战。高度的怀疑指数和及时使用替代成像方式对于在这位复杂患者中取得良好结果至关重要。需要进一步研究以建立在神经调节装置情况下DCM管理的循证推荐。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5940/12270518/d8820d0f153c/cureus-0017-00000086204-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5940/12270518/21d26f52f011/cureus-0017-00000086204-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5940/12270518/0601aa5245d1/cureus-0017-00000086204-i02.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5940/12270518/5e7b5ac50031/cureus-0017-00000086204-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5940/12270518/d8820d0f153c/cureus-0017-00000086204-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5940/12270518/21d26f52f011/cureus-0017-00000086204-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5940/12270518/0601aa5245d1/cureus-0017-00000086204-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5940/12270518/3ddd69bcb04a/cureus-0017-00000086204-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5940/12270518/5e7b5ac50031/cureus-0017-00000086204-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5940/12270518/d8820d0f153c/cureus-0017-00000086204-i05.jpg

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本文引用的文献

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Neurosurgery. 2021 Sep 15;89(4):597-609. doi: 10.1093/neuros/nyab239.
2
Diagnostic Modality in Spine Disease: A Review.脊柱疾病的诊断方式:综述
Asian Spine J. 2020 Dec;14(6):910-920. doi: 10.31616/asj.2020.0593. Epub 2020 Dec 22.
3
Safety and Utility of Spinal Magnetic Resonance Imaging in Patients with High-Frequency Spinal Cord Stimulators: A Prospective Single-Centre Study.高频脊髓刺激器患者脊柱磁共振成像的安全性与实用性:一项前瞻性单中心研究
Stereotact Funct Neurosurg. 2019;97(4):272-277. doi: 10.1159/000503730. Epub 2019 Oct 25.
4
Pathobiology of Degenerative Cervical Myelopathy.退行性颈椎脊髓病的病理生物学
Neurosurg Clin N Am. 2018 Jan;29(1):13-19. doi: 10.1016/j.nec.2017.09.015. Epub 2017 Oct 28.
5
MRI Conditionality in Patients with Spinal Cord Stimulation Devices.脊髓刺激装置患者的MRI条件限制
Stereotact Funct Neurosurg. 2016;94(4):254-258. doi: 10.1159/000448764. Epub 2016 Sep 16.
6
Anterior Cervical Discectomy and Fusion (ACDF): Comparison Between Zero Profile Implants and Anterior Cervical Plate and Spacer.前路颈椎间盘切除融合术(ACDF):零轮廓植入物与前路颈椎钢板及椎间融合器的比较
Cureus. 2016 Apr 17;8(4):e573. doi: 10.7759/cureus.573.
7
Degenerative Cervical Myelopathy: Epidemiology, Genetics, and Pathogenesis.退行性颈椎脊髓病:流行病学、遗传学及发病机制
Spine (Phila Pa 1976). 2015 Jun 15;40(12):E675-93. doi: 10.1097/BRS.0000000000000913.
8
Spinal cord stimulation and pain relief in painful diabetic peripheral neuropathy: a prospective two-center randomized controlled trial.脊髓刺激和疼痛缓解在糖尿病性周围神经痛中的作用:一项前瞻性双中心随机对照试验。
Diabetes Care. 2014 Nov;37(11):3016-24. doi: 10.2337/dc14-0684. Epub 2014 Sep 11.
9
Rapid progressive clinical deterioration of cervical spondylotic myelopathy.脊髓型颈椎病的快速进行性临床恶化。
Spinal Cord. 2015 May;53(5):408-12. doi: 10.1038/sc.2014.137. Epub 2014 Sep 2.
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Stereotact Funct Neurosurg. 2013;91(4):265-9. doi: 10.1159/000346501. Epub 2013 May 7.