Kirven L A, Thornsberry C
Antimicrob Agents Chemother. 1977 Jun;11(6):1004-6. doi: 10.1128/AAC.11.6.1004.
Recent isolates of Neisseria gonorrhoeae have been shown to be resistant to penicillin because they produce beta-lactamase. In this study, conjugal transfer of the beta-lactamase gene to a recipient N. gonorrhoeae strain occurred in one of the two strains studied but not in the other. The transconjugant could also conjugally transfer the beta-lactamase gene to an Escherichia coli strain.
最近分离出的淋病奈瑟菌已被证明对青霉素耐药，因为它们产生β-内酰胺酶。在本研究中，β-内酰胺酶基因在两个受试菌株中的一个中发生了向受体淋病奈瑟菌菌株的接合转移，但在另一个中未发生。转接合子也能将β-内酰胺酶基因接合转移至大肠杆菌菌株。
