Troiano Derek T, Studer Michael H-P
School of Agricultural, Forest, and Food Sciences, Bern University of Applied Sciences, Zollikofen, Switzerland.
Nat Commun. 2025 Jul 21;16(1):6712. doi: 10.1038/s41467-025-61957-x.
There is currently significant interest in employing microbial communities for converting lignocellulosic feedstock into chemicals, fuels, and other products of use to humans. Both naturally occurring microbial communities, which can be prohibitively complex, and synthetic consortia, which are simple though can be unstable and unpredictable, have been employed to that end. Recent work has focused on developing tools for enabling wider application of microbial consortia in both lignocellulose valorization and bioprocesses in general. Together with improved methods of process monitoring and creative process design, newly developed biosynthetic tools may represent key facilitators for commercial realization of consortia-based lignocellulose conversion processes.
目前,人们对利用微生物群落将木质纤维素原料转化为化学品、燃料和其他对人类有用的产品有着浓厚的兴趣。为此,人们既采用了天然存在的微生物群落(其可能极其复杂),也采用了合成菌群(其虽简单但可能不稳定且不可预测)。最近的工作重点是开发工具,以促进微生物群落在木质纤维素增值及一般生物过程中的更广泛应用。与改进的过程监测方法和创新性的过程设计一起,新开发的生物合成工具可能是基于菌群的木质纤维素转化过程实现商业化的关键推动因素。