Lu Yang, Li Fanghe, Wu Qiong, Zhai Qingteng, Li Xinyi, Xie Weibin, Guo Shuwen, Gao Kuo
School of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China.
Institute of Basic Theory for Chinese Medicine, China Academy of Chinese Medical Sciences, Beijing, China.
Front Cardiovasc Med. 2025 Jul 7;12:1547604. doi: 10.3389/fcvm.2025.1547604. eCollection 2025.
Mitochondria, as the powerhouse of myocardial energy metabolism, have garnered considerable interest in the realm of myocardial ischemia (MI) therapy research. The purpose of this study is to illustrate the hot spots and frontiers of mitochondrial research in MI in the past decade through bibliometric analysis.
Both articles and reviews of mitochondrial research in MI from 2015 to 2024 were retrieved from the Web of Science Core Collection database. Bibliometric analysis was performed mainly using CiteSpace and VOSviewer.
The analysis encompassed 4,387 papers. The annual publications exhibited a significant increasing trend, rising from 342 publications in 2015 to 541 publications in 2024. China, the United States of America, and Germany emerged as the top three contributors to MI related mitochondria studies. The Air Force Medical University, China, was the leading publisher. Chattipakorn, Nipon (Chiang Mai University), Chattipakorn, Siriporn C (Chiang Mai University), Zhou, Hao (Zhejiang University) were the top three most active and influential scholars based on the H-index. was the most co-cited journal in this field. Until 2024, the keywords with the strongest citation bursts included mitophagy, transplantation, homeostasis, and myocardial ischemia-reperfusion. The current research trend is to translate mitochondria-related diagnostic and therapeutic drugs for MI into the clinic.
Exploring MI from a mitochondrial perspective has great potential. By revealing the knowledge structure of this field, this study helps to provide scholars in related fields with a comprehensive understanding of the field and develop collaborations.
线粒体作为心肌能量代谢的动力源，在心肌缺血（MI）治疗研究领域引起了广泛关注。本研究旨在通过文献计量分析阐明过去十年MI中线粒体研究的热点和前沿。
从科学网核心合集数据库中检索2015年至2024年有关MI中线粒体研究的文章和综述。主要使用CiteSpace和VOSviewer进行文献计量分析。
分析涵盖4387篇论文。年度出版物呈显著增长趋势，从2015年的342篇增至2024年的541篇。中国、美国和德国是MI相关线粒体研究的前三大贡献国。中国空军军医大学是主要的出版机构。基于H指数，Nipon Chattipakorn（清迈大学）、Siriporn C Chattipakorn（清迈大学）、Hao Zhou（浙江大学）是最活跃且最具影响力的前三位学者。 是该领域被引频次最高的期刊。截至2024年，具有最强引文爆发的关键词包括线粒体自噬、移植、内稳态和心肌缺血再灌注。当前的研究趋势是将MI相关的线粒体诊断和治疗药物转化为临床应用。
从线粒体角度探索MI具有巨大潜力。通过揭示该领域的知识结构，本研究有助于为相关领域的学者提供对该领域的全面理解并促进合作。
