Tay Darren Dean, Kumar Vijay Subbiah, Shapawi Rossita, Shah Muhammad Dawood, Ahmad Hajar Fauzan, Mazlan Nurzafirah
Higher Institution Centres of Excellence, Borneo Marine Research Institute, Universiti Malaysia Sabah, 88400, Kota Kinabalu, Sabah, Malaysia.
Biotechnology Research Institute, University Malaysia Sabah, 88400, Kota Kinabalu, Sabah, Malaysia.
Appl Biochem Biotechnol. 2025 Jul 22. doi: 10.1007/s12010-025-05330-0.
Aquaculture allows the cultivation of aquatic life outside its normal origins which can provide work opportunities, seafood security, as well as conservation efforts for endangered fish species. Numerous factors influence the health of aquaculture fish, with the gut microbiome playing a pivotal role. Research indicates that an imbalance or dysbiosis in the gut microbiome can significantly affect the overall well-being and health outcome of these fish. Despite extensive research utilizing metagenomics across diverse environments and controlled conditions, a clear consensus on the characteristic of "healthy" or "optimal" gut microbiome in domesticated fish has yet to be established. This review will cover 28 studies, which further discusses the findings of the gut microbiome within fish and attempts to provide a general outline of how the gut bacteria may interact and affect fish health within aquaculture environments. The indices as well as pathogens and beneficial bacteria of each study are also listed. This review aims to provide readers with an enhanced understanding of the complex dynamics of the gut microbiome in aquaculture fish, while offering insights that could inform the design of future studies in this field.
水产养殖能够在水生生物的正常产地之外进行养殖，这可以提供工作机会、保障海鲜供应，同时也有助于对濒危鱼类进行保护。众多因素会影响水产养殖鱼类的健康，其中肠道微生物群起着关键作用。研究表明，肠道微生物群的失衡或失调会显著影响这些鱼类的整体健康状况和健康结果。尽管在不同环境和受控条件下利用宏基因组学进行了广泛研究，但对于养殖鱼类中“健康”或“最佳”肠道微生物群的特征尚未达成明确共识。本综述将涵盖28项研究，进一步讨论鱼类肠道微生物群的研究结果，并试图概述肠道细菌在水产养殖环境中可能如何相互作用并影响鱼类健康。还列出了每项研究的指标以及病原体和有益细菌。本综述旨在让读者更好地理解水产养殖鱼类肠道微生物群的复杂动态，同时提供一些见解，为该领域未来的研究设计提供参考。
