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乳牙使用不同器械进行根管预备后的术后疼痛:一项系统评价与Meta分析

Postoperative Pain After Root Canal Preparation With Different Instruments in Primary Teeth: A Systematic Review and Meta-Analysis.

作者信息

Teja Kavalipurapu Venkata, Vasundhara Kaligotla Apoorva, Spagnuolo Gianrico, Cernera Mariangela, Armogida Niccolò Giuseppe, Iaculli Flavia, Rengo Carlo

机构信息

Department of Conservative Dentistry & Endodontics, Mamata Institute of Dental Sciences, Hyderabad, Telangana, India.

Department of Prosthodontics, Saveetha Dental College and Hospitals - Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, India.

出版信息

Clin Exp Dent Res. 2025 Aug;11(4):e70180. doi: 10.1002/cre2.70180.

DOI:10.1002/cre2.70180
PMID:40702914
Abstract

OBJECTIVE

This systematic review and meta-analysis aimed to evaluate the effectiveness of different instrumentation systems in reducing postoperative pain following root canal preparation in primary teeth.

MATERIAL AND METHODS

The present study was conducted in accordance with PRISMA guidelines and registered on PROSPERO (CRD42020135904). The review aimed to determine whether there is a difference in postoperative pain incidence using various instrumentation systems (manual and mechanical) for root canal preparation of primary teeth during pulpectomy. An extensive database search was performed using specific MeSH terms to include clinical studies up to November 2024. Based on eligibility criteria, the selected articles were subjected to quality assessment and the risk of bias was conducted using the Cochrane Risk of Bias (RoB 2) tool. In addition, meta-analyses were conducted on homogeneous studies.

RESULTS

A total of 11 studies were included for qualitative assessments, and 7 studies underwent quantitative analysis. The results review indicated that mechanical instrumentation systems yielded better overall pain reduction compared to manual systems. The meta-analysis further demonstrated statistically significant pain reduction at 6 (p < 0.01, 95% CI: 1.46) and 12 h (p < 0.01, 95% CI: 2.15). However, no notable pain reduction or significance were observed at other time points (p = 0.41, 95% CI: 1.66; p = 0.23, 95% CI: 1.67; p = 0.61, 95% CI: 1.25). The overall risk of bias was low for the included studies.

CONCLUSION

Rotary NiTi instrumentation systems were superior in reducing Postoperative pain incidence in primary teeth undergoing pulpectomy.

CLINICAL RELEVANCE

Mechanical instrumentation is not only advantageous in decreasing overall treatment time, but also in reducing pain incidence after pulpectomy, which nowadays represents an important and widely used procedure to preserve primary teeth.

摘要

目的

本系统评价和荟萃分析旨在评估不同器械系统在降低乳牙根管预备术后疼痛方面的有效性。

材料与方法

本研究按照PRISMA指南进行,并在PROSPERO(CRD42020135904)上注册。该评价旨在确定在乳牙牙髓摘除术中使用各种器械系统(手动和机械)进行根管预备后,术后疼痛发生率是否存在差异。使用特定的医学主题词进行广泛的数据库检索,以纳入截至2024年11月的临床研究。根据纳入标准,对所选文章进行质量评估,并使用Cochrane偏倚风险(RoB 2)工具进行偏倚风险评估。此外,对同类研究进行荟萃分析。

结果

共纳入11项研究进行定性评估,7项研究进行定量分析。结果综述表明,与手动系统相比,机械器械系统在总体疼痛减轻方面效果更好。荟萃分析进一步表明,在6小时(p < 0.01,95%可信区间:1.46)和12小时(p < 0.01,95%可信区间:2.15)时疼痛减轻具有统计学意义。然而,在其他时间点未观察到明显的疼痛减轻或显著性(p = 0.41,95%可信区间:1.66;p = 0.23,95%可信区间:1.67;p = 0.61,95%可信区间:1.25)。纳入研究的总体偏倚风险较低。

结论

旋转镍钛器械系统在降低接受牙髓摘除术的乳牙术后疼痛发生率方面更具优势。

临床意义

机械器械不仅有利于缩短总体治疗时间,还能降低牙髓摘除术后的疼痛发生率,而牙髓摘除术目前是保存乳牙的一项重要且广泛应用的操作。

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本文引用的文献

1
Evaluation of Apically Extruded Debris During Root Canal Preparation Using ProTaper Ultimate and ProTaper Gold: An Ex Vivo Study.使用ProTaper Ultimate和ProTaper Gold进行根管预备时根尖挤出碎屑的评估:一项体外研究
Eur Endod J. 2025 Jan;10(1):41-46. doi: 10.14744/eej.2024.43650.
2
Different outcomes of rotary and manual instrumentation in primary teeth pulpectomy: a systematic review and meta-analysis.乳牙牙髓切断术中旋转器械与手动器械操作的不同结果:一项系统评价与Meta分析
Eur Arch Paediatr Dent. 2025 Mar 24. doi: 10.1007/s40368-025-01020-x.
3
Comparative Evaluation of Apical Debris Extrusion in Primary Molars Using Three Different Pediatric Rotary Systems: An Study.
使用三种不同儿童旋转系统对乳磨牙根尖碎屑挤出情况的比较评估:一项研究。
Int J Clin Pediatr Dent. 2024 Nov;17(11):1224-1228. doi: 10.5005/jp-journals-10005-2989. Epub 2024 Dec 19.
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Evaluation of various root canal irrigation methods in primary teeth: a systematic review.乳牙中各种根管冲洗方法的评估:一项系统评价。
BMC Oral Health. 2024 Dec 21;24(1):1535. doi: 10.1186/s12903-024-05164-y.
5
Comparative analysis of rotary versus manual instrumentation in paediatric pulpectomy procedures: A systematic review and meta-analysis.儿童牙髓切断术操作中旋转器械与手动器械的对比分析:一项系统评价与Meta分析
Aust Endod J. 2025 Apr;51(1):181-196. doi: 10.1111/aej.12899. Epub 2024 Nov 4.
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To Compare and Evaluate Rotary and Manual Techniques in Biomechanical Preparation of Primary Molars to Know Their Effects in Terms of Cleaning and Shaping Efficacy.比较和评估旋转技术与手动技术在乳磨牙生物力学预备中的应用,以了解它们在清洁和成形效果方面的作用。
Int J Clin Pediatr Dent. 2024 Aug;17(8):864-870. doi: 10.5005/jp-journals-10005-2949.
7
Comparative Evaluation of Effectiveness of Rotary and Hand File Systems in Terms of Quality of Obturation and Instrumentation Time among Primary Teeth: A Systematic Review and Meta-analysis of Randomized Controlled Trials.旋转锉系统与手动锉系统在乳牙根管充填质量和操作时间方面有效性的比较评价:一项随机对照试验的系统评价与Meta分析
Int J Clin Pediatr Dent. 2024 Aug;17(8):962-969. doi: 10.5005/jp-journals-10005-2950.
8
Volumetric Analysis of Hand and Rotary Instrumentation, Root Canal Filling Techniques, and Obturation Materials in Primary Teeth Using Spiral CT.使用螺旋 CT 对乳牙进行手用和机用根管预备、根管充填技术以及根管封闭材料的容积分析。
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9
An Evaluation of Postoperative Pain after Root Canal Instrumentation Using Manual K-files and Kedo-S Rotary files in Primary Molars.使用手动K锉和Kedo-S旋转锉对乳磨牙进行根管预备后的术后疼痛评估
J Pharm Bioallied Sci. 2024 Feb;16(Suppl 1):S136-S139. doi: 10.4103/jpbs.jpbs_420_23. Epub 2023 Nov 7.
10
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Eur Arch Paediatr Dent. 2024 Apr;25(2):181-189. doi: 10.1007/s40368-024-00863-0. Epub 2024 Mar 10.