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探索伊拉克患者艾滋病毒管理中的依从性、治疗经历及医疗服务质量:挑战与影响因素

Exploring Adherence, Treatment Experiences, and Quality of Healthcare Services in HIV Management Among Iraqi Patients: Challenges and Influential Factors.

作者信息

Talabani Shlova Najim, Mikhael Ehab Mudher

机构信息

Naser Hospital, Directorate of Health - Kirkuk, Iraqi Ministry of Health, Kirkuk, Iraq.

Clinical Pharmacy Department, College of Pharmacy, University of Baghdad, Baghdad, Iraq.

出版信息

HIV AIDS (Auckl). 2025 Jul 19;17:227-240. doi: 10.2147/HIV.S539087. eCollection 2025.

Abstract

BACKGROUND

Although all antiretroviral therapies reduce viral load, first-line regimens vary slightly in effectiveness and tolerability, often leading to treatment changes. Non-adherence is common in developing countries due to limited-resources and poor patient-provider communication. Data on HIV treatment and adherence are scarce in Iraq.

OBJECTIVE

To obtain in-depth insight into treatment regimens, medication adherence, healthcare quality, and the challenges and factors influencing them among Iraqi HIV patients.

METHODS

A qualitative study utilizing face-to-face interviews was conducted with HIV patients at three HIV centers in Iraq. The interview-guide was developed and validated by a panel of experts. Participants were recruited via convenience and purposive sampling. Interviews, conducted in Arabic, were audio-recorded and lasted 10-20 minutes. Data collection continued until saturation. Data analyzed manually by thematic-analysis approach.

RESULTS

Forty-seven HIV patients were interviewed. Three themes emerged: treatment of HIV, adherence to anti-HIV medications, and accessibility and quality of care for HIV patients. All patients were on a combination pill (Tenofovir-disoproxil, lamivudine, and dolutegravir), but most had changed regimens due to medication shortages or side effects. While most began treatment immediately after diagnosis, delays occurred mainly due to administrative issues, drug unavailability, or side effects. Most patients reported transient initial side effects. Medication adherence was generally good, though many patients missed some doses due to forgetfulness, travel, or medication unavailability. Most patients rated care quality as good, valuing the physician's role in HIV-management. Barriers to accessing care included medication supply interruption and discrimination. Recommendations to improve care included establishing specialized clinics at HIV centers and ensuring continuous medication supply.

CONCLUSION

HIV care in Iraq largely aligns with international guidelines, but administrative delays hinder timely treatment initiation. Adherence is good, though medication supply interruptions and travel are main non-adherence factors. Ensuring continuous medication supply and establishing specialized clinics are essential for improved care.

摘要

背景

尽管所有抗逆转录病毒疗法均可降低病毒载量,但一线治疗方案在有效性和耐受性方面存在细微差异,这常常导致治疗方案的改变。由于资源有限以及患者与医护人员之间沟通不畅,在发展中国家,不坚持治疗的情况很常见。伊拉克关于艾滋病毒治疗和依从性的数据很少。

目的

深入了解伊拉克艾滋病毒患者的治疗方案、药物依从性、医疗质量以及影响这些方面的挑战和因素。

方法

在伊拉克的三个艾滋病毒中心,对艾滋病毒患者进行了一项采用面对面访谈的定性研究。访谈指南由一个专家小组制定并验证。通过便利抽样和目的抽样招募参与者。访谈以阿拉伯语进行,进行了录音,持续10 - 20分钟。数据收集持续到饱和状态。采用主题分析法对数据进行人工分析。

结果

对47名艾滋病毒患者进行了访谈。出现了三个主题:艾滋病毒的治疗、抗艾滋病毒药物的依从性以及艾滋病毒患者获得医疗服务的可及性和质量。所有患者都在服用复方片剂(替诺福韦酯、拉米夫定和多替拉韦),但大多数患者因药物短缺或副作用而改变了治疗方案。虽然大多数患者在诊断后立即开始治疗,但延迟主要是由于行政问题、药物无法获取或副作用。大多数患者报告了最初的短暂副作用。药物依从性总体良好,不过许多患者因遗忘、旅行或药物无法获取而漏服了一些剂量。大多数患者对护理质量评价良好,重视医生在艾滋病毒管理中的作用。获得医疗服务的障碍包括药物供应中断和歧视。改善护理服务的建议包括在艾滋病毒中心设立专科诊所并确保持续的药物供应。

结论

伊拉克的艾滋病毒护理在很大程度上符合国际指南,但行政延迟阻碍了及时开始治疗。依从性良好,不过药物供应中断和旅行是主要的不依从因素。确保持续的药物供应和设立专科诊所对于改善护理服务至关重要。

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