Li Ruijuan, Yang Xueneng, Chen Hanbo, Dong Minglin, Shu Jun, Liu Junfei, Zeng Ming
The Second Affiliated Hospital of Kunming Medical University, Kunming, China.
Front Public Health. 2025 Jul 10;13:1603321. doi: 10.3389/fpubh.2025.1603321. eCollection 2025.
Decubitus ulcers, or pressure injuries, are a growing global health issue, particularly among aging populations. However, comprehensive studies on their burden and trends remain limited.
Using the GBD 2021 database, we analyzed global, regional, and national burdens of decubitus ulcers from 1990 to 2021, including prevalence, incidence, DALYs, and death. Key metrics were assessed through age-standardized rates and absolute counts. Statistical methods such as decomposition analysis and Bayesian age-period-cohort modeling were employed to explore trends and disparities. Future projections were made up to 2040.
While age-standardized prevalence and incidence rates remained stable, DALY and death rates declined globally. Nevertheless, absolute cases, DALYs, and deaths increased significantly, driven by population aging and growth. High-SDI regions showed higher prevalence but lower DALY and death burdens, while low-SDI regions faced severe challenges due to limited resources. Health inequalities persisted, with widening absolute disparities despite narrowing relative inequalities. By 2040, total burden is projected to rise, especially among individuals over 40.
The increasing global burden of decubitus ulcers highlights the need for tailored prevention strategies and resource allocation. These findings offer critical evidence for reducing health disparities and improving global management of this condition.
褥疮，即压力性损伤，是一个日益严重的全球健康问题，在老年人群中尤为突出。然而，关于其负担和趋势的全面研究仍然有限。
我们使用全球疾病负担研究（GBD）2021数据库，分析了1990年至2021年全球、区域和国家层面褥疮的负担情况，包括患病率、发病率、伤残调整生命年（DALYs）和死亡情况。关键指标通过年龄标准化率和绝对计数进行评估。采用分解分析和贝叶斯年龄-时期-队列模型等统计方法来探究趋势和差异。并对2040年之前的情况进行了未来预测。
虽然年龄标准化患病率和发病率保持稳定，但全球伤残调整生命年和死亡率有所下降。然而，由于人口老龄化和增长，绝对病例数、伤残调整生命年数和死亡人数显著增加。高社会人口指数（SDI）地区患病率较高，但伤残调整生命年和死亡负担较低，而低社会人口指数地区由于资源有限面临严峻挑战。健康不平等现象持续存在，尽管相对不平等有所缩小，但绝对差距却在扩大。到2040年，预计总负担将上升，尤其是40岁以上人群。
全球褥疮负担的增加凸显了制定针对性预防策略和资源分配的必要性。这些研究结果为减少健康差距和改善全球对此病症的管理提供了关键证据。
