Personalized Dietary Self-Management and Its Influence on Disease Progression in Chronic Hepatitis B.

Clinical treatment of chronic hepatitis B (CHB) patients nowadays is still focusing on the clearance ratio of HBsAg. However, the quality of the CHB patients' lives and the recovery of their liver organs also need to be considered in the clinic, especially in the nursing field. Here, we evaluated a newly personalized dietary self-management, which emphasized vegetable oil rather than the oneness requirement of a low-oil diet for the patients, accommodating the thinner patient group for their sufficient energy intake. An observational study was conducted with 90 individual CHB patients through the double-arm randomized study method. The newly personalized dietary self-management education was performed among the participants in the refined group, and their physiological detection results after 6 months from enrollment would be compared with those of the control group participants who received traditional dietary self-management education. Compared to the control group with traditional dietary self-management education, we found that the results in the refined group presented a faster reduction speed in ALT, AST, and TBIL. The results of this study showed the benefit of the vegetable oil for CHB patients when it appropriately served as the way of energy intake, during the patients' treatment period. A larger scale of this personalized dietary self-management education should be permitted for further assessment.