Andrae U, Singh J, Ziegler-Skylakakis K
Toxicol Lett. 1985 Nov;28(2-3):93-8. doi: 10.1016/0378-4274(85)90015-3.
Pyruvate efficiently protected V79 Chinese hamster cells against the lethal effects of hydrogen peroxide. Protection was also provided by other alpha-ketoacids, such as alpha-ketobutyrate, alpha-ketoglutarate and alpha-ketoadipate, although higher concentrations were required. The corresponding beta-ketoacids had no effect. The results indicate that pyruvate and other alpha-ketoacids possess antioxidant activity in vitro and, probably, in vivo.
丙酮酸能有效保护V79中国仓鼠细胞免受过氧化氢的致死效应。其他α-酮酸，如α-酮丁酸、α-酮戊二酸和α-酮己二酸也具有保护作用，不过需要更高的浓度。相应的β-酮酸则没有效果。结果表明，丙酮酸和其他α-酮酸在体外可能也在体内具有抗氧化活性。
