Meng Xiaohong, Geng Ruojun, Yang Kaili, Wei Jingjing, Xu Zepeng, Wang Menghan, Ren Shengwei
Nanyang Medical College, Nanyang, 473061, Henan, China.
Henan Provincial People's Hospital, Henan Eye Hospital, Henan Eye Institute, People's Hospital of Zhengzhou University, Henan University People's Hospital, Zhengzhou, 450003, Henan, China.
BMC Ophthalmol. 2025 Jul 28;25(1):425. doi: 10.1186/s12886-025-04255-w.
To compare the suitability of the Standard Patient Evaluation of Eye Dryness (SPEED) and the Ocular Surface Disease Index (OSDI) among Chinese college students, and to further validate the SPEED questionnaire by using the OSDI in a non-clinical sample.
This cross-sectional study involved 1,084 students from Nanyang Medical College, aged 18 to 21 years. The students completed the OSDI and SPEED questionnaires to assess dry eye symptoms. The correlation between the scores of the two questionnaires was analyzed to assess criterion validity. Based on the OSDI scores, a receiver operating characteristic curve was constructed to determine the area under the ROC curve and the cut-off point for evaluating the diagnostic threshold of the SPEED questionnaire.
The Cronbach's alpha values for the OSDI and SPEED questionnaires were 0.943 and 0.911, respectively. Notably, only 281 participants (25.92%) completed all 12 questions in the OSDI questionnaire, whereas all participants completed the SPEED questionnaire without omitting any questions. The mean SPEED scores Full were 3.71, 11.57, 13.84, and 19.72 for each subgroup. Posthoc testing revealed statistically significant differences between all groups (P < 0.05). A significant correlation was observed between the OSDI score, the SPEED score, and the SPEED score Full, particularly between the SPEED score and the SPEED score Full.
In comparison to the OSDI questionnaire, the SPEED questionnaire demonstrates a favorable response rate, reliability, and validity in differentiating dry eye symptoms among Chinese college students. It may be more appropriate for diagnosing dry eye and conducting epidemiological studies within this population.
比较标准干眼患者评估（SPEED）问卷和眼表疾病指数（OSDI）在中国大学生中的适用性，并在非临床样本中使用OSDI进一步验证SPEED问卷。
这项横断面研究纳入了1084名南阳医学高等专科学校18至21岁的学生。学生们完成了OSDI和SPEED问卷以评估干眼症状。分析两份问卷得分之间的相关性以评估效标效度。基于OSDI得分构建受试者工作特征曲线，以确定ROC曲线下面积及评估SPEED问卷诊断阈值的切点。
OSDI和SPEED问卷的Cronbach's alpha值分别为0.943和0.911。值得注意的是，只有281名参与者（25.92%）完成了OSDI问卷中的所有12个问题，而所有参与者都完整完成了SPEED问卷，没有遗漏任何问题。每个亚组的SPEED总分均值分别为3.71、11.57、13.84和19.72。事后检验显示所有组之间存在统计学显著差异（P < 0.05）。观察到OSDI得分、SPEED得分和SPEED总分之间存在显著相关性，特别是SPEED得分与SPEED总分之间。
与OSDI问卷相比，SPEED问卷在区分中国大学生干眼症状方面显示出良好的应答率、可靠性和效度。它可能更适合在此人群中诊断干眼和进行流行病学研究。
