Department of Diagnostics and Microsurgery of Glaucoma, Medical University of Lublin, Chmielna 1, 20-079 Lublin, Poland.
Faculty of Medicine, Medical University of Lublin, 20-059 Lublin, Poland.
Int J Environ Res Public Health. 2023 Jan 11;20(2):1313. doi: 10.3390/ijerph20021313.
Aim: The aim of the study was to demonstrate the prevalence and risk factors of dry eye symptoms (DES) among university students in Poland. Material and methods: A cross-sectional study survey was conducted among 312 Polish university students. The questionnaire consisted of the Ocular Surface Disease Index (OSDI), the 5-Item Dry Eye Questionnaire (DEQ-5) and questions regarding medical history and risk factors. Results: According to the OSDI, more than half of respondents (57.1%) have symptoms of ocular surface disease. Time spent using electronic devices is correlated with scores gathered in both OSDI and DEQ-5 (p < 0.001). There is a statistically significant dependence between psychotropics (p = 0.002), glucocorticosteroids usage (p = 0.026), the presence of depression (p < 0.001), diabetes (p = 0.01) or allergy (p = 0.008) and dry eye symptoms proved in both questionnaires. Respondents with refractive errors and those living in metropolitan areas have a statistically higher symptom intensity(p < 0.022). Stress felt by students is associated with higher DES risk. No correlation between DES and smoking habits was observed. The history of SARS-CoV-2 infection was associated with the severity of DES (p = 0.036). Conclusion: Pathogenesis of DES is multifactorial and its severity depends on several factors, both genetic and environmental. Its prevalence among the young population is underestimated. Determining risk factors will enable the implementation of appropriate prophylaxis and early diagnosis.
本研究旨在展示波兰大学生干眼症状(DES)的患病率和危险因素。
对 312 名波兰大学生进行横断面研究调查。问卷包括眼表疾病指数(OSDI)、五要素干眼问卷(DEQ-5)以及病史和危险因素相关问题。
根据 OSDI,超过一半的受访者(57.1%)有眼表疾病症状。使用电子设备的时间与 OSDI 和 DEQ-5 得分相关(p<0.001)。精神类药物(p=0.002)、糖皮质激素使用(p=0.026)、抑郁(p<0.001)、糖尿病(p=0.01)或过敏(p=0.008)的存在与两种问卷中证实的干眼症状之间存在统计学显著相关性。有屈光不正和居住在大都市区的受访者的症状强度具有统计学意义(p<0.022)。学生的压力与更高的 DES 风险相关。未观察到 DES 与吸烟习惯之间的相关性。SARS-CoV-2 感染史与 DES 严重程度相关(p=0.036)。
DES 的发病机制是多因素的,其严重程度取决于遗传和环境等多种因素。其在年轻人群中的患病率被低估。确定危险因素将有助于实施适当的预防措施和早期诊断。