Jia Ruolin, Yu Xiaowei, Jiang Rong, Zhang Jiaomei, Che Meiling
Department of Reproductive Medicine, Department of Prenatal Diagnosis, The First Hospital of Jilin University, Changchun, Jilin, China.
Department of Anesthesiology, Changchun Central Hospital, Changchun, Jilin, China.
Ann Med. 2025 Dec;57(1):2537918. doi: 10.1080/07853890.2025.2537918. Epub 2025 Jul 29.
To summarize and analyse the ultrasound image characteristics and prognosis of persistent vitelline vein.
The keywords 'vitelline vein' or 'portal vein tumour' were used to search the China Knowledge Network (CNKI), Wipo database, Wanfang database, and Chinese Medical Journal Full Text Database. Pubmed, Embase, and Uptodate databases were searched with the keywords 'vitelline vein' or 'portal vein tumour'. Literature from the above databases up to October 2024 was searched. We summarized the retrieved case data and analysed the pathogenesis, ultrasonographic manifestations, and follow-up prognosis of persistent vitelline veins.
Seventeen relevant English-language publications were retrieved, all in case reports involving 24 patients. Descriptive analysis was used to compare the included cases, and meta-analysis was inappropriate because of the great variation in the quality of the studies.
Persistent vitelline veins are uncommon, with a low prenatal diagnosis rate of 29.2% of available cases, and are mostly diagnosed postnatally. The diagnosis can be made in the prenatal period by a detailed examination of the portal venous system, which is clinically differentiated most notably from umbilical vein dilatation. Once the diagnosis of persistent vitelline veins is made, and it should be closely followed up in the prenatal period. Patient follow-up should be done by a multidisciplinary team and always in preparation for postpartum surgery to prevent acute severe postpartum complications related to thrombosis.
总结并分析永存卵黄静脉的超声图像特征及预后。
使用关键词“卵黄静脉”或“门静脉肿瘤”检索中国知网（CNKI）、Wipo数据库、万方数据库和中国医学期刊全文数据库。使用关键词“卵黄静脉”或“门静脉肿瘤”检索Pubmed、Embase和Uptodate数据库。检索上述数据库截至2024年10月的文献。我们总结检索到的病例数据，并分析永存卵黄静脉的发病机制、超声表现及随访预后。
检索到17篇相关英文文献，均为病例报告，涉及24例患者。采用描述性分析对纳入病例进行比较，由于研究质量差异较大，不适合进行荟萃分析。
永存卵黄静脉较为罕见，产前诊断率低，现有病例中仅为29.2%，大多在出生后诊断。产前通过详细检查门静脉系统可作出诊断，临床上与脐静脉扩张最易鉴别。一旦诊断为永存卵黄静脉，产前应密切随访。患者随访应由多学科团队进行，并始终为产后手术做好准备，以预防与血栓形成相关的急性严重产后并发症。
