Azhary Ayman, Hajhamed Nooh Mohamed, Altyip Ahmed Noralla, Elamin Elham, Ali Eman Taha Osman, Ahmed Ayman, Siddig Emmanuel Edwar
Department of Medical Microbiology, Faculty of Medical Laboratory Sciences, Omdurman Islamic University, Khartoum, Sudan.
Department of Medical Microbiology, Faculty of Medicine, Al Mughtaribeen University, Khartoum, Sudan.
IJID Reg. 2025 Jul 5;16:100700. doi: 10.1016/j.ijregi.2025.100700. eCollection 2025 Sep.
This study assesses the magnitude and epidemiological characteristics of the recent cholera resurgence in Kosti City, Sudan, amid ongoing armed conflict and water supply disruptions.
This was a retrospective cross-sectional study based on hospital records that analyzed cholera surveillance data from Kosti Teaching Hospital from February 20, 2025, to February 24, 2025 (peak period). Epidemiological measures included case fatality rate (CFR) based on the following factors: age, sex, and displacement status. We analyzed the data using R software version 4.2.2.
During the peak period, 1714 cholera cases and 69 fatalities were reported (CFR: 4.02%). 136 individuals were internally displaced, and age groups 1-4 and ≥65 years demonstrated the highest CFRs of 9.7% and 9.9%, respectively. By March 5, 2025, 1004 new cases had overwhelmed Kosti Teaching Hospital, with a lower fatality rate (2.3%) compared to the peak period's CFR.
The resurgence of cholera in Kosti underscores the critical need for strengthened water, sanitation, and hygiene interventions and coordinated outbreak response strategies. Addressing underlying vulnerabilities is essential to prevent future outbreaks, especially in conflict-affected settings.
本研究评估了在苏丹科斯蒂市持续武装冲突和供水中断的情况下，近期霍乱卷土重来的规模和流行病学特征。
这是一项基于医院记录的回顾性横断面研究，分析了2025年2月20日至2025年2月24日（高峰期）科斯蒂教学医院的霍乱监测数据。流行病学指标包括基于年龄、性别和流离失所状况等因素的病死率（CFR）。我们使用R软件版本4.2.2分析数据。
在高峰期，报告了1714例霍乱病例和69例死亡（CFR：4.02%）。136人是境内流离失所者，1 - 4岁年龄组和≥65岁年龄组的病死率最高，分别为9.7%和9.9%。到2025年3月5日，1004例新病例使科斯蒂教学医院不堪重负，病死率（2.3%）低于高峰期的CFR。
科斯蒂霍乱的卷土重来凸显了加强水、环境卫生和个人卫生干预措施以及协调疫情应对策略的迫切需求。解决潜在的脆弱性对于预防未来疫情至关重要，尤其是在受冲突影响的地区。
