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竖脊肌平面阻滞对经椎间孔腰椎椎间融合术中血压变异性、失血量及术后疼痛的影响

Effects of erector spinae plane block on intraoperative blood pressure variability, blood loss, and postoperative pain in transforaminal lumbar interbody fusion.

作者信息

Chen Wei-Cheng, Tsai Hsin-I, Kao Fu-Cheng, Tsai Tsung-Ting, Niu Chi-Chien, Chen Lih-Huei, Lai Po-Liang, Chiu Ping-Yeh

机构信息

Department of Orthopaedic Surgery, Chang Gung Memorial Hospital, Gueishan, Taoyuan, Taiwan.

Department of Anesthesiology, Linkou Chang Gung Memorial Hospital, Taoyuan, Taiwan.

出版信息

Sci Rep. 2025 Jul 29;15(1):27721. doi: 10.1038/s41598-025-13518-x.

Abstract

Erector spinae plane block (ESPB) improves recovery and reduces opioid use, while intraoperative blood pressure variability (IBPV) negatively impacts postoperative outcomes. This study evaluates ESPB's efficacy in reducing IBPV and improving perioperative outcomes in transforaminal lumbar interbody fusion (TLIF). We retrospectively analyzed TLIF patients with and without ESPB from January 2021 to June 2023. ESPB was performed under ultrasonography guidance by anesthesiologists or operators. Intraoperative arterial blood pressure was assessed. Coefficient of variation (CV) and mean arterial pressure difference (MAPD) were calculated as IBPV metrics. Secondary outcomes included blood loss, operation time, postoperative pain, morphine consumption, time to line removal, and discharge. Sixty patients (30 ESPB, 30 non-ESPB) were included, with median ages of 61.3 and 69.5 years, respectively. The ESPB cohort showed significantly lower MAPD (42.0 mmHg vs. 47.1 mmHg, p = 0.02), CV (13.0% vs. 14.7%, p = 0.01), blood loss (268.3 mL vs. 426.7 mL, p < 0.01), and blood loss per level (105.1 mL vs. 157.6 mL, p = 0.02). ESPB also reduced pain in the recovery room (4.7 vs. 6.7, p < 0.01) and on postoperative day 1 (2.3 vs. 2.8, p < 0.01) and accelerated nutritional recovery (1.7 days vs. 3.0 days, p < 0.01). The only complication was observed in the non-ESPB group. ESPB significantly reduced IBPV, blood loss, and postoperative pain in TLIF. It also resulted in lower morphine consumption and earlier mobilization, though these differences did not reach statistical significance. No ESPB-related complications were observed, supporting its safety and its role as an effective component of perioperative management in spine surgery.

摘要

竖脊肌平面阻滞(ESPB)可改善恢复情况并减少阿片类药物的使用,而术中血压变异性(IBPV)会对术后结果产生负面影响。本研究评估ESPB在减少经椎间孔腰椎椎间融合术(TLIF)中IBPV及改善围手术期结果方面的疗效。我们回顾性分析了2021年1月至2023年6月接受TLIF手术且有或无ESPB的患者。ESPB由麻醉医生或手术医生在超声引导下进行。评估术中动脉血压。计算变异系数(CV)和平均动脉压差值(MAPD)作为IBPV指标。次要结果包括失血量、手术时间、术后疼痛、吗啡用量、拔管时间和出院时间。纳入60例患者(30例接受ESPB, 30例未接受ESPB),中位年龄分别为61.3岁和69.5岁。接受ESPB的队列显示MAPD显著更低(42.0 mmHg对47.1 mmHg, p = 0.02)、CV更低(13.0%对14.7%, p = 0.01)、失血量更低(268.3 mL对426.7 mL, p < 0.01)以及每节段失血量更低(105.1 mL对157.6 mL, p = 0.02)。ESPB还减轻了恢复室的疼痛(4.7对6.7, p < 0.01)以及术后第1天的疼痛(2.3对2.8, p < 0.01),并加速了营养恢复(1.7天对3.0天, p < 0.01)。仅在未接受ESPB的组中观察到并发症。ESPB显著降低了TLIF中的IBPV、失血量和术后疼痛。它还使吗啡用量减少且活动更早,尽管这些差异未达到统计学意义。未观察到与ESPB相关的并发症,这支持了其安全性以及它作为脊柱手术围手术期管理有效组成部分的作用。

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