Shahroodi Raha, Norton Jonathan D, Boyd Cynthia M, Steinman Michael A
Division of Geriatrics, University of California San Francisco and the San Francisco VA Medical Center, San Francisco, CA, United States.
Division of Geriatric Medicine and Gerontology, Johns Hopkins University School of Medicine, Baltimore, MA, United States.
Front Med (Lausanne). 2025 Jul 16;12:1622200. doi: 10.3389/fmed.2025.1622200. eCollection 2025.
Deprescribing plays a critical role in ensuring safe and effective healthcare for older adults, including but not limited to those with vulnerabilities such as multimorbidity and dementia, which increase the risk of harm from unnecessary medications. However, much is unknown on how to safely and effectively stop medications. In response, the US Deprescribing Research Network (USDeN) was created with a mission of enhancing the quality, volume, and real-world impact of research aimed at optimizing medication use among older adults. This Perspective explores the rationale for its creation, the principles and ideas that animate its work, its impacts on research, and future directions for deprescribing research. By advancing research in this area, we aim to improve healthcare outcomes and reduce medication-related harm among older adults.
减药在确保老年人获得安全有效的医疗保健方面发挥着关键作用，这些老年人包括但不限于患有多种疾病和痴呆症等易损病症的患者，这些病症会增加不必要药物带来伤害的风险。然而，关于如何安全有效地停用药物，仍有很多未知之处。作为回应，美国减药研究网络（USDeN）应运而生，其使命是提高旨在优化老年人用药的研究的质量、数量和实际影响力。本观点文章探讨了其成立的理由、推动其工作的原则和理念、其对研究的影响以及减药研究的未来方向。通过推进该领域的研究，我们旨在改善老年人的医疗保健结果并减少与药物相关的伤害。
